CAS 105139-98-8

7-(2-hydroxyethoxy)mitosane

Description:

7-(2-Hydroxyethoxy)mitosane, with the CAS number 105139-98-8, is a synthetic compound that belongs to the class of mitosanes, which are known for their potential applications in cancer therapy due to their ability to interfere with cellular processes. This compound features a hydroxyl group and an ethoxy group, which contribute to its solubility and reactivity. The presence of the hydroxyethoxy moiety may enhance its pharmacological properties, such as improving bioavailability or modulating interactions with biological targets. Mitosanes generally exhibit cytotoxic effects, making them of interest in the development of chemotherapeutic agents. The specific characteristics of 7-(2-hydroxyethoxy)mitosane, such as its molecular weight, melting point, and solubility, would typically be determined through experimental methods. Additionally, its mechanism of action, potential side effects, and therapeutic efficacy would be subjects of ongoing research, particularly in the context of targeted cancer treatments. Overall, this compound represents a significant area of study in medicinal chemistry and pharmacology.

Formula: C₁₇H₂₁N₃O₇

InChI: InChI=1/C17H21N3O7/c1-7-12(22)11-10(13(23)14(7)26-4-3-21)8(6-27-16(18)24)17(25-2)15-9(19-15)5-20(11)17/h8-9,15,19,21H,3-6H2,1-2H3,(H2,18,24)/t8?,9-,15?,17?/m0/s1

Synonyms:

• 6-(2-Hydroxyethoxy-6-deaminomitomycin C)
• [(1aS)-6-(2-hydroxyethoxy)-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate
• Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-6-(2-hydroxyethoxy)-8a-methoxy-5-methyl-, (1aS-(1aalpha,8beta,8aalpha,8balpha))-
• 7-(2-Hydroxyethoxy)mitosane
• Bmy 25551
• Bmy-25551

BMY-25551

CAS: 105139-98-8

BMY-25551, a Mitomycin A analog, exhibits cytotoxicity 8 to 20 times greater than Mitomycin C against both murine and human tumor cell lines. It is applicable in research pertaining to cancer and hematological disorders.

Formula: C₁₇H₂₁N₃O₇

Color and Shape: Solid

Molecular weight: 379.36

Ref: TM-T201024