CAS 1051418-95-1

Nevirapine-d4

Description:

Nevirapine-d4 is a deuterated form of nevirapine, which is an antiretroviral medication primarily used in the treatment of HIV infection. The "d4" designation indicates that four hydrogen atoms in the nevirapine molecule have been replaced with deuterium, a stable isotope of hydrogen. This modification can enhance the compound's stability and alter its pharmacokinetic properties, making it useful in research applications, particularly in studies involving drug metabolism and pharmacodynamics. Nevirapine itself is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that works by binding to the reverse transcriptase enzyme, preventing the conversion of viral RNA into DNA, thereby inhibiting viral replication. The chemical structure of nevirapine-d4 retains the core features of nevirapine, including its aromatic rings and functional groups, but with the added mass of deuterium, which can be detected using mass spectrometry. This compound is primarily utilized in scientific research rather than clinical settings, providing insights into drug interactions and the behavior of antiretroviral therapies in biological systems.

Formula: C₁₅H₁₄N₄O

Synonyms:

• Nevirapine methyl D4
• Nevirapine-d4
• d4-11-cyclopropyl-4-methyl-5H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6(11H)-one
• Nevirapine-d4 (cyclopropyl-2,2,3,3-d4)
• B2Nevirapine-d4

Nevirapine-d4

CAS: 1051418-95-1

Formula: C₁₅H₁₀D₄N₄O

Color and Shape: White To Off-White Solid

Molecular weight: 270.33

Ref: 4Z-N-223

Nevirapine-d4 (cyclopropyl-2,2,3,3-d4)(Nevirapine)

CAS: 1051418-95-1

Purity: 99 atom % D

Molecular weight: 270.33

Ref: 3U-D7554

Nevirapine-d4 (cyclopropyl-2,2,3,3-d4)

Controlled Product

CAS: 1051418-95-1

Applications Nevirapine-d4 (cyclopropyl-2,2,3,3-d4) (CAS# 1051418-95-1) is a useful isotopically labeled research compound. This can be prepared to use as non-nucleoside reverse transcriptase inhibitors.
References Gant, T., et.al., PCT Int.Appl., 113,(2008);

Formula: C₁₅D₄H₁₀N₄O

Color and Shape: Neat

Molecular weight: 270.33

Ref: TR-N391281

Nevirapine-d4

CAS: 1051418-95-1

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Formula: C₁₅H₁₄N₄O

Purity: Min. 95%

Molecular weight: 270.32 g/mol

Ref: 3D-BSB41895