CAS 1051419-24-9

11-Cyclopropyl-5,11-dihydro-4-(methyl-d3)-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one

Description:

11-Cyclopropyl-5,11-dihydro-4-(methyl-d3)-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one is a complex organic compound characterized by its unique bicyclic structure, which incorporates both diazepine and pyridine rings. This compound features a cyclopropyl group, contributing to its three-membered ring structure, and a deuterated methyl group, indicating the presence of heavy hydrogen isotopes, which can influence its physical and chemical properties. The presence of nitrogen atoms in the diazepine and pyridine rings suggests potential basicity and reactivity, making it of interest in medicinal chemistry. Its structural complexity may confer specific biological activities, potentially making it a candidate for pharmaceutical applications. The compound's CAS number, 1051419-24-9, allows for precise identification and retrieval of information in chemical databases. Overall, this substance exemplifies the intricate nature of organic compounds and their potential utility in various chemical and biological contexts.

Formula: C₁₅H₁₁D₃N₄O

InChI: InChI=1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20)/i1D3

InChI key: InChIKey=NQDJXKOVJZTUJA-FIBGUPNXSA-N

SMILES: C(C1=C2C(N(C=3C(C(=O)N2)=CC=CN3)C4CC4)=NC=C1)([2H])([2H])[2H]

Synonyms:

• 6H-Dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one, 11-cyclopropyl-5,11-dihydro-4-(methyl-d3)-
• 11-Cyclopropyl-5,11-dihydro-4-(methyl-d3)-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one
• Nevarapine-d3
• NEVIRAPINE-D3
• 11-Cyclopropyl-5,11-dihydro-4-(methyl-d
• )-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
• 11-Cyclopropyl-5,11-dihydro-4-Methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one-d3
• BI-RG 587-d3
• [2H3]-Nevirapine
• 3
• NSC 641530-d3

Nevirapine-d3

Controlled Product

CAS: 1051419-24-9

Applications Labelled Nevirapine (N391275), a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. Antiviral.
References Hargrave, K.D., et al.: J. Med. Chem., 34, 2231 (1991), Cheeseman, S.H., et al.: Antimicrob. Agents Chemother., 37, 178 (1993), Guay, L.A., et al.: Lancet, 354, 795 (1999),

Formula: C₁₅H₁₁D₃N₄O

Color and Shape: White To Light Beige

Molecular weight: 269.32

Ref: TR-N391278

Nevirapine-d3

CAS: 1051419-24-9

Nevirapine-d3 is a deuterated compound of Nevirapine. Nevirapine has a CAS number of 129618-40-2. Nevirapine is a benzodiazepine non-nucleoside reverse transcriptase inhibitor. In combination with other antiretroviral drugs, nevirapine reduces HIV viral loads and increases CD4 counts, thereby retarding or preventing the damage to the immune system and reducing the risk of developing AIDS.

Formula: C₁₅H₁₁D₃N₄O

Molecular weight: 269.32

Ref: TM-TMID-0206