CAS 1051463-24-1

Cobicistat Impurity 9 DiHCl

CAS: 1051463-24-1

Formula: C₈H₁₄N₂OS·2HCl

Molecular weight: 186.28 2*36.46

Ref: 4Z-C-122017

α,α-Dimethyl-4-[(methylamino)methyl]-2-thiazolemethanol Hydrochloride

Controlled Product

CAS: 1051463-24-1

Applications A Cobicistat (C633150) impurity. Cobicistat is a HIV protease inhibitor and have been coadministered with low-dose ritonavir (R535000) as a pharmacoenhancer, significantly increasing their plasma concentrations.
References Von, H., Exp. Rev. Clin. Pharmacol., 5, 557 (2012); Lepist, E.I., et al.: Antimicrob. Agent. Chemother., 56, 5409 (2012); Orr, S.T.M., et al.: J. Med. Chem., 55, 4896 (2012);

Formula: C₈H₁₅ClN₂OS

Color and Shape: Neat

Molecular weight: 222.74

Ref: TR-D474700

α,α-Dimethyl-4-[(methylamino)methyl]-2-thiazolemethanol hydrochloride

CAS: 1051463-24-1

α,α-Dimethyl-4-[(methylamino)methyl]-2-thiazolemethanol hydrochloride is a synthetic intermediate of the drug product. It is an impurity in the API and metabolite of the drug. It is a high purity analytical standard that can be used to establish HPLC retention time and to confirm purity by GC/MS. It also has niche applications as a pharmacopoeia impurity standard or as a custom synthesis.

Formula: C₈H₁₄N₂OS

Purity: Min. 95%

Molecular weight: 186.28 g/mol

Ref: 3D-BSB46324

Cobicistat Impurity 1

CAS: 1051463-24-1

Formula: C₈H₁₄N₂OS

Molecular weight: 186.3

Ref: ST-EA-CP-C131007