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CAS 1051970-61-6

:

(Des-Gly10,D-Leu6,Orn8,Pro-NHEt9)-LHRH

Description:
The chemical substance known as (Des-Gly10,D-Leu6,Orn8,Pro-NHEt9)-LHRH, with the CAS number 1051970-61-6, is a synthetic analog of luteinizing hormone-releasing hormone (LHRH), which plays a crucial role in the regulation of reproductive hormones. This compound is characterized by specific modifications to its amino acid sequence, including the substitution of glycine, leucine, ornithine, and proline, which enhance its stability and biological activity compared to the natural hormone. The presence of the N-ethyl group at the ninth position contributes to its pharmacological properties, potentially increasing its potency and duration of action. As a peptide, it exhibits properties typical of such compounds, including solubility in water and susceptibility to enzymatic degradation. Its primary applications are in the fields of endocrinology and reproductive medicine, particularly in the treatment of hormone-sensitive conditions. Overall, this compound exemplifies the strategic modifications made to peptide hormones to improve therapeutic efficacy.
Formula:C58H82N14O12
Synonyms:
  • Pyr-His-Trp-Ser-Tyr-D-Leu-Leu-Orn-Pro-NHEt
  • 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-ornithyl-N-ethyl-L-prolinamide
  • (Orn8)-Leuprolide, (Orn8)-Leuprorelin
  • (Des-Gly10,D-Leu6,Orn8,Pro-NHEt9)-LHRH
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