CAS 105310-47-2

(E)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride

Description:

(E)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride, with the CAS number 105310-47-2, is a chemical compound characterized by its unique cyclopropane structure, which contributes to its potential biological activity. This substance features an amine functional group, indicating the presence of nitrogen, which can participate in hydrogen bonding and influence its solubility and reactivity. The diethyl substituents on the nitrogen atom suggest that it may exhibit lipophilic properties, potentially affecting its pharmacokinetics. The phenyl group attached to the cyclopropane ring can enhance its interaction with biological targets, making it of interest in medicinal chemistry. As a hydrochloride salt, it is likely to be more soluble in water compared to its free base form, facilitating its use in various applications, including pharmaceuticals. The stereochemistry indicated by the (E) configuration suggests specific spatial arrangements that may be crucial for its biological activity. Overall, this compound's structural features position it as a candidate for further investigation in drug development and related fields.

Formula: C₁₅H₂₃ClN₂O

InChI: InChI=1/C15H22N2O.ClH/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12;/h5-9,13H,3-4,10-11,16H2,1-2H3;1H/t13-,15-;/m0./s1

SMILES: CCN(CC)C(=O)[C@@]1(C[C@H]1CN)c1ccccc1.Cl

Synonyms:

• Cyclopropanecarboxamide, 2-(aminomethyl)-N,N-diethyl-1-phenyl-, (E)-, monohydrochloride
• [(1R,2R)-2-(diethylcarbamoyl)-2-phenylcyclopropyl]methanaminium chloride

trans-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride

CAS: 105310-47-2

Formula: C₁₅H₂₃ClN₂O

Purity: 97%

Color and Shape: Solid

Molecular weight: 282.8089

Ref: IN-DA008UA8

(±)-trans Milnacipran HCl

CAS: 105310-47-2

Formula: C₁₅H₂₂N₂O·HCl

Color and Shape: Off-White Solid

Molecular weight: 246.35 36.46

Ref: 4Z-M-4133

rac,trans-Milnacipran Hydrochloride

Controlled Product

CAS: 105310-47-2

Applications rac,trans-Milnacipran Hydrochloride is an impurity of rac-Milnacipran Hydrochloride (M344600), an antidepressant and a selective norepinephrine and serotonin reuptake inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Moret, C., et al.: Neuropharmacology, 24, 1211 (1985), Palmier, C., et al.: Eur. J. Clin. Pharmacol., 37, 235 (1989), Spencer, C.M., et al.: Drugs, 56, 405 (1998)

Formula: C₁₅H₂₃ClN₂O

Color and Shape: Neat

Molecular weight: 282.81

Ref: TR-M344625

(±)-trans Milnacipran

CAS: 105310-47-2

Formula: C₁₅H₂₂N₂OHCl

Molecular weight: 246.35 : 36.46

Ref: ST-EA-CP-M47022

(E)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamideHydrochloride

Controlled Product

CAS: 105310-47-2

Levomilnacipran is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used for the treatment of major depressive disorder and fibromyalgia. It has been shown to have antidepressant effects in patients with major depressive disorder and fibromyalgia. Levomilnacipran inhibits the reuptake of serotonin and norepinephrine by blocking the transporter proteins in these neurotransmitter pathways, increasing their availability to interact with receptors in the brain. Levomilnacipran also has been found to inhibit aminotransferase activity, which may be responsible for its hepatotoxicity.

Formula: C₁₅H₂₃ClN₂O

Purity: Min. 95%

Molecular weight: 282.81 g/mol

Ref: 3D-FA150604