CAS 105350-26-3

2-[[3-(2-QUINOLINYLMETHOXY)PHENYL]AMINO]BENZOIC ACID HYDROCHLORIDE

Description:

2-[[3-(2-Quinolinylmethoxy)phenyl]amino]benzoic acid hydrochloride, with the CAS number 105350-26-3, is a chemical compound characterized by its complex structure, which includes a benzoic acid moiety, an amino group, and a quinoline-derived substituent. This compound typically appears as a white to off-white solid and is soluble in polar solvents, such as water and methanol, due to the presence of the carboxylic acid and amino functional groups. It may exhibit biological activity, potentially serving as a pharmaceutical agent or research chemical, particularly in studies related to medicinal chemistry or pharmacology. The hydrochloride salt form enhances its stability and solubility, making it more suitable for various applications. As with many organic compounds, it is essential to handle this substance with care, following appropriate safety protocols, as it may pose health risks if ingested or improperly handled. Its specific reactivity and interactions would depend on the functional groups present and the conditions under which it is used.

Formula: C₂₃H₁₈N₂O₃

InChI: InChI=1/C23H18N2O3/c26-23(27)20-9-2-4-11-22(20)24-17-7-5-8-19(14-17)28-15-18-13-12-16-6-1-3-10-21(16)25-18/h1-14,24H,15H2,(H,26,27)

SMILES: c1ccc2c(c1)ccc(COc1cccc(c1)Nc1ccccc1C(=O)O)n2

Synonyms:

• Sr 2640 Hydrochloride
• SR2640HCl
• 2-[3-(2-Quinolylmethoxy)phenylamino]benzoic acid hydrochloride
• 2-{[3-(Quinolin-2-Ylmethoxy)Phenyl]Amino}Benzoic Acid

SR2640

CAS: 105350-26-3

SR2640 is a potent and highly selective LTD4/LTE4 antagonist, specifically inhibiting LTD4-induced contractions in guinea pig ileum and tracheal smooth muscle in a concentration-dependent manner, without affecting histamine-induced contractions. It blocks the binding of 0.4 nM [3H]LTD4 to guinea pig lung membrane receptors with an IC50 of 23 nM. SR2640 also causes a parallel rightward shift in the dose-response curve for LTD4-induced bronchoconstriction in guinea pigs when administered intravenously, with the degree of shift correlating positively with its dosage. SR2640 is applicable for asthma research.

Formula: C₂₃H₁₈N₂O₃

Color and Shape: Solid

Molecular weight: 370.401

Ref: TM-T204567