CAS 1054-88-2

Spiroxatrine

Description:

Spiroxatrine, with the CAS number 1054-88-2, is a chemical compound that belongs to the class of anticholinergic agents. It is primarily recognized for its use in the treatment of various respiratory conditions, particularly as a bronchodilator. The compound functions by inhibiting the action of acetylcholine at muscarinic receptors, leading to relaxation of bronchial smooth muscle and subsequent dilation of the airways. Spiroxatrine is characterized by its relatively low solubility in water, which influences its pharmacokinetic properties, including absorption and distribution in the body. The compound exhibits a moderate half-life, allowing for effective dosing regimens. Additionally, it may have side effects typical of anticholinergic drugs, such as dry mouth, blurred vision, and urinary retention. Its chemical structure features a spirocyclic moiety, contributing to its unique pharmacological profile. Overall, spiroxatrine is an important agent in respiratory therapy, although its use may be limited by potential side effects and the availability of alternative treatments.

Formula: C₂₂H₂₅N₃O₃

InChI: InChI=1S/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26)

InChI key: InChIKey=JVGBTTIJPBFLTE-UHFFFAOYSA-N

SMILES: O=C1C2(N(CN1)C3=CC=CC=C3)CCN(CC4OC=5C(OC4)=CC=CC5)CC2

Synonyms:

• 1,3,8-Trianaspiro(4.5)decane-4-one,8-(1,4-benzodioxan-2-ylmethyl)-1-phenyl-
• 1,3,8-Triazaspiro[4.5]decan-4-one, 8-(1,4-benzodioxan-2-ylmethyl)-1-phenyl-
• 1,3,8-Triazaspiro[4.5]decan-4-one, 8-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-
• 1,4-Benzodioxin, 1,3,8-triazaspiro[4.5]decan-4-one deriv.
• 8-(1,4-Benzodioxan-2-ylmethyl)-1-phenyl-1,3,8-trianaspiro(4,5)decane-4-one
• 8-(1,4-Benzodioxan-2-ylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
• 8-(2,3-Dihydro-1,4-Benzodioxin-2-Ylmethyl)-1-Phenyl-1,3,8-Triazaspiro[4.5]Decan-4-One
• 8-[(2,3-Dihydro-1,4-benzodioxin-2-yl)methyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
• Espiroxatrina
• Espiroxatrina [INN-Spanish]
• Nsc 665322
• R 5188
• Spiroxatrine [INN]
• Spiroxatrinum
• Spiroxatrinum [INN-Latin]
• Unii-Dr0Qr50All

Spiroxatrine

CAS: 1054-88-2

Spiroxatrine

Purity: ≥98%

Molecular weight: 379.45g/mol

Ref: 54-BUP06308

Spiroxatrine

CAS: 1054-88-2

Spiroxatrine (R 5188) is a 5-HT1α and α2-adrenergic dual antagonist with sedative activity for the study of diseases related to the cardiovascular system.

Formula: C₂₂H₂₅N₃O₃

Purity: 99.94%

Color and Shape: Solid

Molecular weight: 379.45

Ref: TM-T23382

Spiroxatrine (R 5188)

Controlled Product

CAS: 1054-88-2

Formula: C₂₂H₂₅N₃O₃

Color and Shape: Neat

Molecular weight: 379.452

Ref: TR-S683503