CAS 10540-29-1
:Tamoxifen
Description:
Tamoxifen is a synthetic non-steroidal compound primarily used in the treatment and prevention of estrogen receptor-positive breast cancer. It functions as a selective estrogen receptor modulator (SERM), exhibiting both estrogenic and anti-estrogenic properties depending on the target tissue. Chemically, Tamoxifen is characterized by its biphenyl structure, which allows it to bind to estrogen receptors, thereby inhibiting the effects of estrogen in breast tissue while potentially exerting estrogen-like effects in other tissues, such as bone and the endometrium. Its molecular formula is C26H29NO, and it has a relatively high lipophilicity, which aids in its absorption and distribution in the body. Tamoxifen is typically administered orally and is known for its side effects, which can include hot flashes, risk of thromboembolic events, and potential endometrial changes. Due to its mechanism of action, Tamoxifen has been a cornerstone in breast cancer therapy, particularly for premenopausal women, and continues to be a subject of research for its broader implications in cancer treatment and prevention.
Formula:C26H29NO
InChI:InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-
InChI key:InChIKey=NKANXQFJJICGDU-QPLCGJKRSA-N
SMILES:C(=C(/CC)\C1=CC=CC=C1)(\C2=CC=C(OCCN(C)C)C=C2)/C3=CC=CC=C3
Synonyms:- (Z)-2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine
- 2-[4-[(1Z)-1,2-Diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethylethanamine
- 2-{4-[(1E)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine
- 2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine
- 2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate (salt)
- Ethanamine, 2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethyl-, (Z)-
- Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-
- Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethyl-
- Ethylamine, 2-[p-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethyl-, (Z)-
- Genox
- Ici 47699
- Kessar
- Mammaton
- Nolvadex
- Nolvadex-D
- Novaldex
- Tamoxen
- Tamoxifen Free Base
- Tamoxifen and its salts
- Tamoxifene
- Tamoxifeno
- Z-Tamoxifen
- See more synonyms
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Found 12 products.
Tamoxifen Citrate
CAS:Formula:C26H29NO·C6H8O7Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:563.65Tamoxifen, 98%
CAS:<p>Tamoxifen, 10540-29-1, is an antineoplastic agent that acts by competitively binding estrogen receptors to reduce DNA synthesis. Learn more at Thermo Fisher Scientific.</p>Formula:C26H29NOPurity:98%Color and Shape:Powder, White to pale creamMolecular weight:371.52Tamoxifen
CAS:Tamoxifen is an orally active selective estrogen receptor modulator (SERM) that acts as an estrogen antagonist in breast cells and an agonist in bone, liver, and uterine cells. It can be used to induce gene knockout and liver injury models in mice, and also exhibits multiple biological activities, including activation of Hsp90, induction of autophagy and apoptosis, and inhibition of EBOV and MARV viral infections.Formula:C26H29NOPurity:98.46% - 99.92%Color and Shape:Fine Off-White Crystalline PowderMolecular weight:371.51Tamoxifen
CAS:Formula:C26H29NOPurity:≥ 99.0%Color and Shape:White to off-white crystalline powderMolecular weight:371.52Tamoxifen EP Impurity F-d5 HCl (N-Desmethyl Tamoxifen-d5 HCl)
CAS:Formula:C25H22D5NO·HClMolecular weight:362.53 36.46Tamoxifen
CAS:Controlled Product<p>Estrogen receptor modulator; protein kinase C inhibitor</p>Formula:C26H29NOPurity:Min. 90%Color and Shape:White PowderMolecular weight:371.51 g/molTamoxifen - Bio-X ™
CAS:Controlled Product<p>Tamoxifen is used as an antineoplastic agent in the treatment of breast cancer. Tamoxifen has been shown to be a competitive antagonist at the estrogen receptor, preventing estrogen from binding and activating it. <br>Tamoxifen is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>Formula:C26H29NOPurity:(%) Min. 95%Color and Shape:PowderMolecular weight:371.51 g/molTamoxifen (1 mg/mL in Methanol)
CAS:Controlled ProductFormula:C26H29NOColor and Shape:ColourlessMolecular weight:371.52trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine
CAS:Controlled Product<p>2,4-Diphenyl-1-butenylphenoxyN,N-dimethylethylamine (2DPB) is a natural compound that has been shown to have cytotoxic effects in breast cancer cell lines. 2DPB is a selective estrogen receptor modulator (SERM) that binds to the estrogen receptor and alters its shape, which blocks the binding of estrogens. 2DPB has also been shown to have antiestrogenic activity in human breast cancer tissues. The drug has been studied as a potential treatment for breast cancer because it targets the estrogen receptor and prevents the growth of tumor cells in preclinical models. This drug is currently being investigated for its effects on tumor suppression and prevention of recurrence.</p>Formula:C26H29NOPurity:Min. 98.0 Area-%Molecular weight:371.51 g/mol
![trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb%2FW-108788.jpg&w=3840&q=75)
