CAS 105405-51-4: 1,2-Distearoyl-sn-glycero-3-phosphatidic acid . disodium salt

Description:1,2-Distearoyl-sn-glycero-3-phosphatidic acid disodium salt, commonly referred to as DSPA, is a phospholipid characterized by its two long-chain fatty acid tails, specifically stearic acid, which contribute to its hydrophobic properties. This compound features a glycerol backbone esterified with two stearoyl groups and a phosphate group, which is further neutralized by two sodium ions, enhancing its solubility in aqueous environments. DSPA is amphiphilic, meaning it possesses both hydrophilic (water-attracting) and hydrophobic (water-repelling) regions, making it an important component in the formation of lipid bilayers and vesicles. It is often utilized in biochemistry and pharmaceutical applications, particularly in drug delivery systems and liposome formulation, due to its ability to encapsulate hydrophobic drugs and facilitate their transport across biological membranes. Additionally, its structural properties allow it to play a role in cell membrane dynamics and signaling processes. Overall, DSPA is a versatile compound with significant implications in both research and therapeutic contexts.

Formula:C₃H₇₅Na₂O₈P