CAS 105454-04-4
:7-Epitaxol
Description:
7-Epitaxol, with the CAS number 105454-04-4, is a synthetic derivative of the natural compound paclitaxel, which is known for its anticancer properties. This compound is characterized by its complex polycyclic structure, which includes a taxane core that is essential for its biological activity. 7-Epitaxol exhibits a similar mechanism of action to paclitaxel, primarily functioning as a microtubule stabilizer, thereby inhibiting cell division and promoting apoptosis in cancer cells. Its efficacy is often evaluated in various cancer types, including breast and ovarian cancers. The compound is typically administered in a formulation that enhances its solubility and bioavailability, as it is poorly soluble in water. Additionally, 7-Epitaxol may have different pharmacokinetic properties compared to paclitaxel, potentially leading to variations in therapeutic outcomes and side effects. Ongoing research aims to better understand its full range of biological activities and potential applications in cancer therapy.
Formula:C47H51NO14
InChI:InChI=1/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32+,33+,35-,36+,37+,38-,40-,45+,46-,47+/m0/s1
InChI key:InChIKey=RCINICONZNJXQF-LYTKHFMESA-N
SMILES:O(C(C)=O)[C@]12[C@]3([C@H](OC(=O)C4=CC=CC=C4)[C@@]5(O)C(C)(C)C([C@@H](OC(C)=O)C(=O)[C@]3(C)[C@H](O)C[C@]1(OC2)[H])=C(C)[C@@H](OC([C@@H]([C@@H](NC(=O)C6=CC=CC=C6)C7=CC=CC=C7)O)=O)C5)[H]
Synonyms:- (2alpha,5beta,7alpha,10beta,13alpha)-4,10-bis(acetyloxy)-13-{[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}-1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
- 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.
- 7-Epipaclitaxel
- 7-epi-Paclitaxel
- 7-epi-Taxol
- Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, (2aR,4R,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)- 2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (alphaR,betaS)-
- Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR- (2aalpha,4alpha,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,12alpha,12aalpha,12balpha))-
- Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4R,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
- Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4α,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-
- Epitaxol
- 7-Epitaxol
- Paclitaxel EP impurity E
- 7-EpipaclitaxelQ: What is
- 7-EPIPACLITAXEL; 7-EPITAXOL; 7-EPI-PACLITAXEL; EPITAXOL
- 7-Epi Paclitaxel (Paclitaxel EP Impurity E)
- Paclitaxel Impurity 5（Paclitaxel EP Impurity E）
- Paclitaxel Impurity E (7-epi Paclitaxel)
- 7-Epipaclitaxel Q: What is the storage condition of
- 7-Epipaclitaxel, 98%, from Taxus chinensis (Pilg.) Rehder
- Propanedioicacid,2-(2-propyn-6-yl)-,diethylester
- Paclitaxel Impurity E
- Paclitaxel 7-Epi-Impurity
- 7-Epipaclitaxel(crude)
- 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete benzenepropanoic acid derivative
- 7-Epipaclitaxel Q: What is the CAS Number of
- Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4α,4aβ,6β
- Paclitaxel EP Impurity E (7-epi Paclitaxel)
- EPITAXOL, 7-
- 7-epi-Paclitaxel(7-Epitaxol)
- Paclitaxel Impurity Ⅲ:(7-Epi-Paclitaxel)
- Benzenepropanoicacid,beta-(benzoylaMino)-alpha-hydroxy-,6,12B-bis(acetyloxy)-12-(benzoyloxy)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-dodecahydro-4,11-dihydroxy-4A,8,13,13-tetraMethyl-5-oxo-7,11-Methano-1H-cyclodeca(3,4)benz(1,2-B)oxet-9-ylester,(2ar-(
- 7-Epipaclitaxel, froM Taxus chinensis
- Paclitaxel Impurity E (7-Diverse Taxol)
- inhibit,Microtubule/Tubulin,7 epi Taxol,7epiTaxol,Inhibitor
- See more synonyms
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Found 10 products.
Paclitaxel EP Impurity E (7-epi Paclitaxel)
CAS:Formula:C47H51NO14Color and Shape:Pale Pink SolidMolecular weight:853.927-Epitaxol
CAS:Formula:C47H51NO14Purity:≥ 98.0%Color and Shape:White to off-white powderMolecular weight:853.927-epi-Taxol
CAS:<p>1.</p>Formula:C47H51NO14Purity:99.32% - 99.93%Color and Shape:SolidMolecular weight:853.917-Epi Paclitaxel
CAS:Controlled ProductFormula:C47H51NO14Color and Shape:Off-WhiteMolecular weight:853.917-epi-Taxol
CAS:<p>Paclitaxel is an anticancer drug that belongs to the class of taxanes. Paclitaxel binds to cell membranes and interferes with cell division by preventing the polymerization of microtubule proteins. This drug can be prepared by high-performance liquid chromatography (HPLC) and has minimal toxicity in humans, but is highly toxic in rats. Paclitaxel also inhibits glucose uptake in breast cancer cells, leading to significant cytotoxicity. It has inhibitory properties against toll-like receptor 4, which may contribute to its anti-inflammatory effects.</p>Formula:C47H51NO14Purity:Min. 95%Color and Shape:PowderMolecular weight:853.91 g/mol
