CAS 105518-68-1
:5-azidouridine-5'-triphosphate
Description:
5-Azidouridine-5'-triphosphate (5-Azido-UTP) is a nucleotide analog characterized by the presence of an azido group at the 5-position of the uridine base. This modification imparts unique properties to the molecule, making it useful in various biochemical applications, particularly in the study of RNA synthesis and function. The triphosphate moiety allows it to participate in enzymatic reactions similar to natural nucleotides, enabling its incorporation into RNA strands during transcription. The azido group can undergo click chemistry reactions, facilitating the labeling and visualization of RNA molecules in cellular studies. Additionally, 5-Azidouridine-5'-triphosphate is often employed in the synthesis of modified RNA for therapeutic and research purposes, including the development of RNA-based drugs and probes. Its stability and reactivity under physiological conditions make it a valuable tool in molecular biology and biochemistry. However, as with any chemical substance, appropriate safety measures should be taken when handling it in laboratory settings.
Formula:C9H14N5O15P3
InChI:InChI=1/C9H14N5O15P3/c10-13-12-3-1-14(9(18)11-7(3)17)8-6(16)5(15)4(27-8)2-26-31(22,23)29-32(24,25)28-30(19,20)21/h1,4-6,8,15-16H,2H2,(H,22,23)(H,24,25)(H,11,17,18)(H2,19,20,21)/t4-,5-,6-,8+/m1/s1
Synonyms:- 5-A-Utp
- Uridine, 5'-(tetrahydrogen triphosphate), 5-azido-
- 5-Azidouridine 5'-(Tetrahydrogen Triphosphate)
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