CAS 105558-26-7

Ginsenoside Rh3

Description:

Ginsenoside Rh3 is a natural compound classified as a triterpenoid saponin, primarily derived from ginseng, a plant known for its medicinal properties. It is one of the many ginsenosides, which are bioactive constituents believed to contribute to the health benefits of ginseng. Ginsenoside Rh3 is characterized by its complex molecular structure, which includes a steroid-like backbone with multiple hydroxyl groups, contributing to its solubility and biological activity. This compound has garnered attention for its potential pharmacological effects, including anti-inflammatory, antioxidant, and neuroprotective properties. Research suggests that Ginsenoside Rh3 may influence various signaling pathways, promoting cellular health and exhibiting potential therapeutic effects in conditions such as cancer and neurodegenerative diseases. Additionally, it is often studied in the context of traditional medicine and modern pharmacology, highlighting its significance in both historical and contemporary health practices. As with many natural products, the efficacy and safety of Ginsenoside Rh3 are subjects of ongoing research, emphasizing the need for further studies to fully understand its mechanisms and applications.

Formula: C₃₆H₆₀O₇

InChI: InChI=1/C36H60O7/c1-20(2)10-9-11-21(3)22-12-16-36(8)28(22)23(38)18-26-34(6)15-14-27(33(4,5)25(34)13-17-35(26,36)7)43-32-31(41)30(40)29(39)24(19-37)42-32/h10-11,22-32,37-41H,9,12-19H2,1-8H3/b21-11-/t22-,23+,24-,25?,26?,27?,28+,29-,30+,31-,32+,34+,35-,36+/m1/s1

InChI key: InChIKey=PHLXREOMFNVWOH-YAGNRYSRSA-N

SMILES: C[C@]12[C@@]([C@]3(C)[C@@](CC1)(C(C)(C)[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)CC3)[H])(C[C@@H](O)[C@]5([C@@]2(C)CC[C@@H]5\C(=C/CC=C(C)C)\C)[H])[H]

Synonyms:

• (3β,12β,20Z)-12-Hydroxydammara-20(22),24-dien-3-yl β-<span class="text-smallcaps">D</span>-glucopyranoside
• (5xi,9xi,12alpha,14beta,20Z)-12-hydroxydammara-20(22),24-dien-3-yl beta-D-glucopyranoside
• Ginsenoside Rh₃
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, (3β,12β,20Z)-12-hydroxydammara-20(22),24-dien-3-yl
• (3β,12β,20Z)-12-Hydroxydammara-20(22),24-dien-3-yl β-D-glucopyranoside
• β-D-Glucopyranoside, (3β,12β,20Z)-12-hydroxydammara-20(22),24-dien-3-yl
• Ginsenoside Rh3
• (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(8R,10R,12S,13R,14S,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2Z)-6-methylhepta-2,5-dien-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol
• 20(S)-Ginsenoside Rh3, 98%, from panax ginseng C. A. Mey.
• ginsenoside Rh3 USP/EP/BP
• [(20Z)-12β-Hydroxy-5α-dammara-20(22),24-dien-3β-yl]β-D-glucopyranoside

Ginsenoside Rh3

CAS: 105558-26-7

Ginsenoside Rh3 is a natural product extracted from Ginseng C. A. Mey.Ginsenoside Rh3 has antifungal and antioxidant activities and induces Nrf2 activation in human retinal cells.

Formula: C₃₆H₆₀O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 604.86

Ref: TM-TQ0199

Ginsenoside Rh3

CAS: 105558-26-7

Formula: C₃₆H₆₀O₇

Molecular weight: 604.87

Ref: 7W-GY0380

Ginsenoside Rh3

CAS: 105558-26-7

Ginsenoside Rh3

Purity: ≥98%

Molecular weight: 604.86g/mol

Ref: 54-BUP21978

Ginsenoside Rh3

CAS: 105558-26-7

Ginsenoside Rh3 is a bacterial metabolite of Rg5, which is the main constituent of heat-processed ginseng, has anti-inflammatory effect in microglia by modulating AMPK and its downstream signaling pathways.

Formula: C₃₆H₆₀O₇

Purity: 95%~99%

Color and Shape: White powder

Molecular weight: 604.869

Ref: BP-BP0669

Ginsenoside Rh3

CAS: 105558-26-7

Ginsenoside Rh3 is a bioactive saponin compound, which is a principle component isolated from Panax ginseng, a perennial plant widely known for its medicinal properties. This compound represents a specific form of ginsenoside with distinct pharmacological characteristics derived through the deglycosylation process of other ginsenosides during processing or digestion.

Formula: C₃₆H₆₀O₇

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 604.86 g/mol

Ref: 3D-OG31927

Ginsenoside Rh3

Controlled Product

CAS: 105558-26-7

Applications Ginsenoside Rh3 is an inhibitor of the NLRP3 and AIM2 inflammasome activation.
References Kim, J., et al.: 158, 143-150 (2014)

Formula: C₃₆H₆₀O₇

Color and Shape: Neat

Molecular weight: 604.86

Ref: TR-G410245

ginsenoside Rh3

CAS: 105558-26-7

Formula: C₃₆H₆₀O₇

Color and Shape: Solid

Molecular weight: 604.8574

Ref: IN-DA008RNK