CAS 105565-55-7

ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE

Description:

Alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazinebutanol hydrochloride, with CAS number 105565-55-7, is a chemical compound characterized by its complex structure, which includes a piperazine ring and multiple fluorinated aromatic groups. This compound is typically classified as a pharmaceutical intermediate or active ingredient, often explored for its potential therapeutic applications, particularly in the field of psychiatry and neurology. The presence of fluorine atoms in its structure may enhance its lipophilicity and metabolic stability, which are desirable properties in drug design. The hydrochloride salt form indicates that it is likely to be more soluble in water, facilitating its use in various formulations. As with many piperazine derivatives, it may exhibit interactions with neurotransmitter systems, making it a subject of interest in research related to mood disorders or other neurological conditions. Safety and handling precautions are essential, as with all chemical substances, due to potential toxicity or reactivity.

Formula: C₁₈H₂₃ClF₂N₄O

InChI: InChI=1/C18H22F2N4O.ClH/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18;/h3-6,12-13,17,25H,1-2,7-11H2;1H

SMILES: C(CC(c1ccc(cc1)F)O)CN1CCN(CC1)c1ncc(cn1)F.Cl

Synonyms:

• Bmy 14802 Hydrochloride
• BMY14802HyClHCl
• 1-(4-Fluorophenyl)-4-[4-(5-Fluoropyrimidin-2-Yl)Piperazin-1-Yl]Butan-1-Ol Hydrochloride

BMY-14802 hydrochloride

CAS: 105565-55-7

BMY-14802 hydrochloride

Purity: ≥98%

Molecular weight: 384.85g/mol

Ref: 54-BUP06343

α-(4-Fluorophenyl)-4-(5-Fluoro-2-Pyrimidinyl)-1-Piperazine Butanol

CAS: 105565-55-7

Alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol (FPPBP) is a ligand that binds to the dopamine D2 receptor and has been shown to have therapeutic effects in Parkinson's disease. FPPBP is a synthetic compound that is being investigated as a potential treatment for this disease. It also has antipsychotic properties and can be used to treat symptoms of schizophrenia. Alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol has been shown to inhibit the activity of hydroxylase, which converts dopamine into norepinephrine, and thus may contribute to its antipsychotic properties. This drug also inhibits the enzyme responsible for converting dopamine into 3,4-dihydroxyphenylalanine (DOPA), thereby inhibiting the synthesis of dopamine in the brain cells.

Formula: C₁₈H₂₃ClF₂N₄O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 384.85 g/mol

Ref: 3D-FF100977

BMY-14802 hydrochloride

CAS: 105565-55-7

BMY-14802 hydrochloride (BMS 181100 hydrochloride) is a selective antagonist of σ receptor (IC50 = 112 nM) with antipsychotic effects.

Formula: C₁₈H₂₃ClF₂N₄O

Purity: 99.97%

Color and Shape: Solid

Molecular weight: 384.85

Ref: TM-T22612