CAS 105565-56-8

α-(4-Fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazinebutanol

Description:

α-(4-Fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazinebutanol, with the CAS number 105565-56-8, is a chemical compound that belongs to the class of piperazine derivatives. This substance features a piperazine ring, which is a six-membered heterocyclic compound containing two nitrogen atoms. The presence of fluorine atoms in both the phenyl and pyrimidine rings enhances its biological activity and lipophilicity, potentially influencing its pharmacokinetic properties. The butanol moiety contributes to its solubility characteristics, making it suitable for various applications in medicinal chemistry. This compound may exhibit activity as a pharmaceutical agent, particularly in the context of central nervous system disorders, due to its structural similarity to known psychoactive substances. Its specific interactions with biological targets, such as receptors or enzymes, would depend on its three-dimensional conformation and electronic properties. As with many synthetic compounds, safety and toxicity profiles would need to be evaluated through rigorous testing to determine its suitability for therapeutic use.

Formula: C₁₈H₂₂F₂N₄O

InChI: InChI=1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2

InChI key: InChIKey=ZXUYYZPJUGQHLQ-UHFFFAOYSA-N

SMILES: C(CCC(O)C1=CC=C(F)C=C1)N2CCN(CC2)C=3N=CC(F)=CN3

Synonyms:

• ( -)-Bms 14802
• 1-(4-Fluorophenyl)-4-[4-(5-Fluoropyrimidin-2-Yl)Piperazin-1-Yl]Butan-1-Ol
• 1-Piperazinebutanol, alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-
• 1-Piperazinebutanol, α-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-
• Bms 181100
• Bmy 14802
• α-(4-Fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazinebutanol

BMY-14802

CAS: 105565-56-8

BMY-14802

Purity: ≥98%

Molecular weight: 348.39g/mol

Ref: 54-BUP06964

BMY-14802

CAS: 105565-56-8

BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.

Formula: C₁₈H₂₂F₂N₄O

Purity: 99.84%

Color and Shape: Soild

Molecular weight: 348.39

Ref: TM-T67739