CAS 105613-48-7

Exametazime

Description:

Exametazime, with the CAS number 105613-48-7, is a radiopharmaceutical compound primarily used in medical imaging, particularly in single-photon emission computed tomography (SPECT) for brain perfusion studies. It is a derivative of hexamethylpropyleneamine oxime (HMPAO) and is characterized by its ability to cross the blood-brain barrier, allowing for the visualization of cerebral blood flow. Exametazime is typically labeled with technetium-99m, a widely used radioisotope in nuclear medicine, which provides the necessary gamma emissions for imaging. The compound is known for its stability and favorable pharmacokinetics, making it effective for diagnostic purposes. In terms of safety, it is generally well-tolerated, although, like all radiopharmaceuticals, it requires careful handling and administration to minimize radiation exposure. Its use is crucial in diagnosing various neurological conditions, including dementia and stroke, by providing valuable insights into brain activity and blood flow dynamics.

Formula: C₁₃H₂₈N₄O₂

InChI: InChI=1/C13H28N4O2/c1-9(11(3)16-18)14-7-13(5,6)8-15-10(2)12(4)17-19/h9-10,14-15,18-19H,7-8H2,1-6H3/b16-11+,17-12+/t9-,10-/m1/s1

InChI key: InChIKey=BPNZYADGDZPRTK-VMBPJTDLNA-N

SMILES: C(CN[C@@H](/C(=N/O)/C)C)(CN[C@@H](/C(=N/O)/C)C)(C)C

Synonyms:

• (+-)-(3RS,3'RS)-3,3'-((2,2-Dimethyltrimethylene)diimino)di-2-butanone (E,E)-dioxime
• 2-Butanone, 3,3'-((2,2-dimethyl-1,3-propanediyl)diimino)bis-, dioxime, (R*,R*-(E,E))-(+-)-
• 2-Butanone, 3,3'-((2,2-dimethyl-1,3-propanediyl)diimino)bis-dioxime-(sup 99m)Tc
• 2-Butanone, 3,3′-[(2,2-dimethyl-1,3-propanediyl)diimino]bis-, 2,2′-dioxime, (2E,2′E,3R,3′R)-rel-
• 2-Butanone, 3,3′-[(2,2-dimethyl-1,3-propanediyl)diimino]bis-, dioxime, (2E,2′E,3R,3′R)-rel-
• 2-​ Butanone, 3,​ 3'-​ [(2,​ 2-​ dimethyl-​ 1,​ 3-​ propanediyl)​ diimino]​ bis-​ , 2,​ 2'-​ dioxime, (2E,​ 2'E,​ 3R,​ 3'R)​ -​ rel-
• Ceretec
• Exametazima
• Exametazima [Spanish]
• Exametazimum
• Exametazimum [Latin]
• Hexametazime
• Hexametazine
• Hexamethylpropylene amine oxide
• Hmpao
• N,N'-bis[(2R,3E)-3-(hydroxyimino)butan-2-yl]-2,2-dimethylpropane-1,3-diamine
• Technetium Tc99m Exametazime
• Unii-G29272Nckl
• d,1-Hexamethylpropylene amine oxime-(sup 99m)Tc
• dl-HMPAO
• dl-Hexamethylpropylene amine oxide
• Exametazime
• 2-Butanone, 3,3'-[(2,2-dimethyl-1,3-propanediyl)diimino]bis-, 2,2'-dioxime, (2E,2'E,3R,3'R)-rel-
• Meso-rich exametazime CRS

MESO-RICH EXAMETAZIME CRS

CAS: 105613-48-7

MESO-RICH EXAMETAZIME CRS

Formula: C₁₃H₂₈N₄O₂

Molecular weight: 272.387

Ref: 41-Y0000227

Exametazime-d6

CAS: 105613-48-7

Formula: C₁₃H₂₂D₆N₄O₂

Molecular weight: 278.43

Ref: 4Z-E-001002

Exametazime

CAS: 105613-48-7

Formula: C₁₃H₂₈N₄O₂

Molecular weight: 272.3930

Ref: 4Z-E-001001

Hexametazine

Controlled Product

CAS: 105613-48-7

Formula: C₁₃H₂₈N₄O₂

Color and Shape: Neat

Molecular weight: 272.39

Ref: TR-H293575