CAS 105613-48-7: Exametazime

Description: Exametazime, with the CAS number 105613-48-7, is a radiopharmaceutical compound primarily used in medical imaging, particularly in single-photon emission computed tomography (SPECT) for brain perfusion studies. It is a derivative of hexamethylpropyleneamine oxime (HMPAO) and is characterized by its ability to cross the blood-brain barrier, allowing for the visualization of cerebral blood flow. Exametazime is typically labeled with technetium-99m, a widely used radioisotope in nuclear medicine, which provides the necessary gamma emissions for imaging. The compound is known for its stability and favorable pharmacokinetics, making it effective for diagnostic purposes. In terms of safety, it is generally well-tolerated, although, like all radiopharmaceuticals, it requires careful handling and administration to minimize radiation exposure. Its use is crucial in diagnosing various neurological conditions, including dementia and stroke, by providing valuable insights into brain activity and blood flow dynamics.

Formula: C₁₃H₂₈N₄O₂

InChI: InChI=1/C13H28N4O2/c1-9(11(3)16-18)14-7-13(5,6)8-15-10(2)12(4)17-19/h9-10,14-15,18-19H,7-8H2,1-6H3/b16-11+,17-12+/t9-,10-/s2

InChI key: InChIKey=BPNZYADGDZPRTK-VMBPJTDLNA-N

SMILES: ON=C(C)C(NCC(C)(C)CNC(C(=NO)C)C)C

Synonyms:

• (+-)-(3RS,3'RS)-3,3'-((2,2-Dimethyltrimethylene)diimino)di-2-butanone (E,E)-dioxime
• 2-Butanone, 3,3'-((2,2-dimethyl-1,3-propanediyl)diimino)bis-, dioxime, (R*,R*-(E,E))-(+-)-
• 2-Butanone, 3,3'-((2,2-dimethyl-1,3-propanediyl)diimino)bis-dioxime-(sup 99m)Tc
• 2-Butanone, 3,3′-[(2,2-dimethyl-1,3-propanediyl)diimino]bis-, 2,2′-dioxime, (2E,2′E,3R,3′R)-rel-
• 2-Butanone, 3,3′-[(2,2-dimethyl-1,3-propanediyl)diimino]bis-, dioxime, (2E,2′E,3R,3′R)-rel-
• 2-​ Butanone, 3,​ 3'-​ [(2,​ 2-​ dimethyl-​ 1,​ 3-​ propanediyl)​ diimino]​ bis-​ , 2,​ 2'-​ dioxime, (2E,​ 2'E,​ 3R,​ 3'R)​ -​ rel-
• Ceretec
• Exametazima
• Exametazima [Spanish]
• Exametazimum
• Exametazimum [Latin]
• Hexametazime
• Hexametazine
• Hexamethylpropylene amine oxide
• Hmpao
• N,N'-bis[(2R,3E)-3-(hydroxyimino)butan-2-yl]-2,2-dimethylpropane-1,3-diamine
• Technetium Tc99m Exametazime
• Unii-G29272Nckl
• d,1-Hexamethylpropylene amine oxime-(sup 99m)Tc
• dl-HMPAO
• dl-Hexamethylpropylene amine oxide
• Exametazime

Meso-rich exametazime CRS

CAS: 105613-48-7

• Formula: C₁₃H₂₈N₄O₂
• Molecular weight: 272.387

Exametazime-d6

CAS: 105613-48-7

• Formula: C₁₃H₂₂D₆N₄O₂
• Molecular weight: 278.43

Exametazime

CAS: 105613-48-7

• Formula: C₁₃H₂₈N₄O₂
• Molecular weight: 272.3930

Hexametazine

CAS: 105613-48-7

• Formula: C₁₃H₂₈N₄O₂
• Color and Shape: Neat
• Molecular weight: 272.39

Exametazime

CAS: 105613-48-7

Exametazime is a diagnostic agent used in the diagnosis of inflammatory bowel disease. It is …

• Formula: C₁₃H₂₈N₄O₂
• Purity: Min. 95%
• Molecular weight: 272.39 g/mol