CAS 105613-90-9

(1-oxopropoxy)-, S-(fluoromethyl)ester, (6α,11β,16α,17α)-

Description:

The chemical substance known as "(1-oxopropoxy)-, S-(fluoromethyl)ester, (6α,11β,16α,17α)-" with the CAS number 105613-90-9 is a synthetic compound that belongs to a class of molecules characterized by specific functional groups and stereochemistry. This compound features an ester functional group, which is indicative of its potential reactivity and solubility properties. The presence of a fluoromethyl group suggests enhanced lipophilicity and may influence biological activity, making it of interest in medicinal chemistry. The stereochemical descriptors (6α,11β,16α,17α) indicate a specific three-dimensional arrangement of atoms, which is crucial for the compound's interaction with biological targets. Such stereochemistry can significantly affect the pharmacokinetics and pharmacodynamics of the substance. Overall, this compound may have applications in pharmaceuticals or agrochemicals, but its specific characteristics, including solubility, stability, and biological activity, would require further investigation through experimental studies.

Formula: C₂₅H₃₃F₃O₅S

Synonyms:

• 6,9-Difluoro-11-Hydroxy-16-Methyl-3-Oxo-17-
• Androst-4-ene-17-carbothioic acid
• Androst-4-ene-17-carbothioic acid,6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-,S-(fluoromethyl) ester,(6α,11β,16α,17α)
• 1,2-Dihydro Fluticasone Propionate
• (1-oxopropoxy)-, S-(fluoromethyl)ester, (6α,11β,16α,17α)-
• Fluticasone Propionate EP Impurity E/1,2-Dihydro Fluticasone Propionate/6α,9-Difluoro-17-[[(fluoromethyl)sulphanyl]carbonyl]-11β-hydroxy-16α-methyl-3-oxoandrost-4-en-17α-yl propanoate
• (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ylpropionate
• Fluticasone Propinate EP impurity E
• Fluticasone Propionate EP Impurity E
• (6α,8ξ,11β,14ξ,16α,17α)-6,9-Difluoro-17-{[(fluoromethyl)sulfanyl] carbonyl}-11-hydroxy-16-methyl-3-oxoandrost-4-en-17-yl propionate
• Androst-4-ene-17-carbothioic acid, 6,9-difluoro-11-hydroxy- 16-Methyl-3-oxo-17-(1- oxopropoxy)-, S-(fluoroMethyl) ester, (6α,11β,16α,17α)-
• 6α,9-difluoro-17-[[(fluoromethyl)sulfanyl]carbonyl]- 11β-hydroxy-16α-methyl-3-oxoandrost-4-en-17α-yl propanoate
• Fluticasone Impurity 5(Fluticasone EP Impurity E)
• Androst-4-ene-17-carbothioicacid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-,S-(fluoromethyl) ester, (6a,11b,16a,17a)- (9CI)
• Fluticasone Furoate Impurity J

1,2-Dihydro Fluticasone Propionate

CAS: 105613-90-9

Organo-sulfur compounds, nesoi

Formula: C₂₅H₃₃F₃O₅S

Color and Shape: White Off-White Solid

Molecular weight: 502.20008

Ref: 45-1A01030

Fluticasone Propionate EP Impurity E

CAS: 105613-90-9

Formula: C₂₅H₃₃F₃O₅S

Color and Shape: White To Off-White Solid

Molecular weight: 502.59

Ref: 4Z-F-099

Fluticasone Propionate EP Impurity E

CAS: 105613-90-9

Formula: C₂₅H₃₃F₃O₅S

Molecular weight: 502.59

Ref: ST-EA-CP-F23005

1,2-Dihydro Fluticasone Propionate

CAS: 105613-90-9

Impurity Fluticasone EP Impurity E
Stability Hygroscopic
Applications 1,2-Dihydro Fluticasone Propionate is an impurity of Fluticasone Propionate (F599500), a derivative of Flumethasone (F455000). An antiallergic; anti-asthmatic; anti-inflammatory.
References Matuszewski, B, et al.: Anal. Chem., 75, 3019 (2003), Fekete, S., et al.: J. Pharm. Biomed. Anal., 49, 64 (2009), Meltzer, E.O., et al.: J. Allergy Clin. Immunol., 86, 221 (1990), Mitchison, H.C., et al.: Gut, 32, 260 (1991), Phillipps, G.H., et al.: J. Med. Chem., 37, 3717 (1994)

Formula: C₂₅H₃₃F₃O₅S

Color and Shape: Neat

Molecular weight: 502.59

Ref: TR-D449635

1,2-Dihydro Fluticasone Propionate-d3

Controlled Product

CAS: 105613-90-9

Formula: C₂₅D₃H₃₀F₃O₅S

Color and Shape: Neat

Molecular weight: 505.605

Ref: TR-D449637