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Fasudil hydrochloride

CAS 105628-07-7: Fasudil hydrochloride

Description:Fasudil hydrochloride is a pharmacological agent primarily recognized for its role as a selective inhibitor of Rho-kinase, which is involved in various cellular processes, including smooth muscle contraction and cell migration. This compound is often utilized in the treatment of conditions such as cerebral vasospasm following subarachnoid hemorrhage and has shown potential in other therapeutic areas, including neuroprotection and cardiovascular diseases. Chemically, Fasudil hydrochloride is characterized by its molecular formula, which reflects its structure and functional groups, contributing to its biological activity. It is typically administered in its hydrochloride salt form, enhancing its solubility and bioavailability. The substance exhibits a moderate to high affinity for Rho-kinase, leading to vasodilation and improved blood flow. Additionally, Fasudil hydrochloride has been studied for its effects on various signaling pathways, making it a subject of interest in research related to cell motility and proliferation. As with any pharmacological agent, its use is accompanied by potential side effects and contraindications, necessitating careful consideration in clinical applications.

Formula:C14H17N3O2S·ClH

InChI:InChI=1S/C14H17N3O2S.ClH/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14;/h1,3-5,7,11,15H,2,6,8-10H2;1H

InChI key:InChIKey=LFVPBERIVUNMGV-UHFFFAOYSA-N

SMILES:Cl.O=S(=O)(C1=CC=CC=2C=NC=CC21)N3CCNCCC3

  • Synonyms:
  • 1-(5-Isoquinolinesulfinyl)hexahydro-1H-1,4-diazepine hydrochloride
  • 1-(5-Isoquinolinesulfonyl)homopiperazine hydrochloride
  • 1H-1,4-Diazepine, hexahydro-1-(5-isoquinolinylsulfonyl)-, monohydrochloride
  • Fasudil HCL
  • Hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine monohydrochloride
  • Isoquinoline, 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride (1:1)
  • Eril
  • Fasudil hydrochloride
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Found 9 products.

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Ref: 3B-F0839

100mg95.00 €
Estimated delivery in United States, on Tuesday 25 Feb 2025
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Fasudil monohydrochloride, 99+%

CAS:105628-07-7

Ref: 02-J60751

1gTo inquire
250mgTo inquire
500mgTo inquire
Estimated delivery in United States, on Wednesday 26 Feb 2025
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Ref: IN-DA00HAO6

1g89.00 €
5g189.00 €
10g290.00 €
25g569.00 €
100mg42.00 €
250mg47.00 €
500mg67.00 €
Estimated delivery in United States, on Tuesday 4 Mar 2025
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Fasudil HCl

CAS:105628-07-7

Ref: 4Z-F-612

5mgTo inquire
10mgTo inquire
25mgTo inquire
50mgTo inquire
100mgTo inquire
Estimated delivery in United States, on Wednesday 5 Mar 2025
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Fasudil Monohydrochloride Salt

CAS:105628-07-7

Ref: 54-BIF105

1g180.00 €
250mg127.00 €
500mg154.00 €
Estimated delivery in United States, on Tuesday 11 Mar 2025
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Fasudil hydrochloride

CAS:105628-07-7

Ref: TM-T3060

50mg42.00 €
100mg49.00 €
200mg74.00 €
500mg96.00 €
1mL*10mM (DMSO)55.00 €
Estimated delivery in United States, on Tuesday 11 Mar 2025
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Fasudil Monohydrochloride Salt

CAS:105628-07-7

Ref: TR-F150018

1g177.00 €
250mg89.00 €
500mg108.00 €
Estimated delivery in United States, on Friday 14 Mar 2025
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Ref: 10-F050724

1g86.00 €
5gTo inquire
25gTo inquire
Estimated delivery in United States, on Friday 14 Mar 2025
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Fasudil hydrochloride

CAS:105628-07-7

Ref: 3D-FF31090

1g390.00 €
2g621.00 €
5g911.00 €
10g1,393.00 €
500mg236.00 €
Estimated delivery in United States, on Monday 17 Mar 2025
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