CAS 1056636-06-6

Momelotinib sulfate

CAS: 1056636-06-6

Momelotinib sulfate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.

Formula: C₂₃H₂₆N₆O₁₀S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 610.62

Ref: TM-T15038

Momelotinib sulfate

CAS: 1056636-06-6

Momelotinib sulfate is a nucleoside that inhibits the tumor necrosis factor (TNF) receptor-associated protein 1 (TRAF1). It has been shown to be effective in treating thrombocytopenia, myeloproliferative neoplasms and myelofibrosis. Momelotinib sulfate has shown promising results in clinical trials for the treatment of myeloproliferative neoplasms and myelofibrosis. The drug works by inhibiting TNF-related apoptosis-inducing ligand (TRAIL) or its receptor, TRAF1. It also inhibits the production of interferon, which can increase the severity of some types of cancer.

Formula: C₂₃H₂₆N₆O₁₀S₂

Purity: Min. 95%

Molecular weight: 610.62 g/mol

Ref: 3D-GSB63606