CAS 105687-81-8

26-homo-1,25-dihydroxyvitamin D3

Description:

26-Homo-1,25-dihydroxyvitamin D3, identified by its CAS number 105687-81-8, is a synthetic analog of vitamin D3, specifically designed to explore the biological effects of vitamin D metabolites. This compound features a modified side chain at the 26th carbon position, which alters its interaction with vitamin D receptors. Like other vitamin D derivatives, it plays a crucial role in calcium and phosphate metabolism, influencing bone health and immune function. Its structural modifications may enhance its potency or alter its pharmacokinetics compared to natural vitamin D3. The compound is primarily studied for its potential therapeutic applications in conditions related to vitamin D deficiency, such as osteoporosis and certain autoimmune diseases. Additionally, its unique characteristics make it a valuable tool in research aimed at understanding the broader implications of vitamin D signaling in various biological processes. As with many vitamin D analogs, the safety profile and efficacy in clinical settings are subjects of ongoing investigation.

Formula: C₂₈H₄₆O₃

InChI: InChI=1/C28H46O3/c1-6-27(4,31)15-7-9-19(2)24-13-14-25-21(10-8-16-28(24,25)5)11-12-22-17-23(29)18-26(30)20(22)3/h11-12,19,23-26,29-31H,3,6-10,13-18H2,1-2,4-5H3/b21-11+,22-12-/t19-,23+,24+,25+,26-,27?,28-/m1/s1

Synonyms:

• 26-Homo-calcitriol
• 27-Nor-9,7-secocholesta-5,7,10(19)triene-1,3,25-triol,25-ethyl-, (1alpha,3beta,5Z,7E)-
• (1S,3R,5Z)-5-[(2E)-2-{(1S,3aS,7aR)-1-[(1R)-5-hydroxy-1,5-dimethylheptyl]-7a-methyloctahydro-4H-inden-4-ylidene}ethylidene]-4-methylidenecyclohexane-1,3-diol (non-preferred name)
• 26-Homo-1,25-dihydroxyvitamin D3

26-Homo-1,25-dihydroxyvitamin D3

Controlled Product

CAS: 105687-81-8

Formula: C₂₈H₄₆O₃

Color and Shape: Neat

Molecular weight: 430.663

Ref: TR-H589510