CAS 105737-62-0

2-Hydroxy-5-[2-[[2-hydroxy-3-[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenoxy]propyl]amino]ethoxy]benzamide methanesulfonate (1:1)

Description:

2-Hydroxy-5-[2-[[2-hydroxy-3-[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenoxy]propyl]amino]ethoxy]benzamide methanesulfonate (1:1), with CAS number 105737-62-0, is a complex organic compound characterized by its multifunctional structure, which includes hydroxy, amino, and sulfonate groups. This compound is typically used in pharmaceutical applications, particularly as a therapeutic agent due to its potential biological activity. The presence of the trifluoromethyl group enhances lipophilicity, which can influence its pharmacokinetic properties. The imidazole ring contributes to its ability to interact with biological targets, making it relevant in medicinal chemistry. Additionally, the methanesulfonate moiety may enhance solubility in aqueous environments, facilitating its use in formulations. Overall, this compound exemplifies the intricate design often found in drug development, where various functional groups are strategically incorporated to optimize efficacy and safety profiles.

Formula: C₂₃H₂₅F₃N₄O₅·CH₄O₃S

InChI: InChI=1S/C23H25F3N4O5.CH4O3S/c1-30-12-20(23(24,25)26)29-22(30)14-2-4-16(5-3-14)35-13-15(31)11-28-8-9-34-17-6-7-19(32)18(10-17)21(27)33;1-5(2,3)4/h2-7,10,12,15,28,31-32H,8-9,11,13H2,1H3,(H2,27,33);1H3,(H,2,3,4)

InChI key: InChIKey=VFPOVCXWKBYDNF-UHFFFAOYSA-N

SMILES: CN1C(=NC(C(F)(F)F)=C1)C2=CC=C(OCC(CNCCOC3=CC(C(N)=O)=C(O)C=C3)O)C=C2.S(C)(=O)(=O)O

Synonyms:

• (±)-2-Hydroxy-5-[2-[[2-hydroxy-3-[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenoxy]propyl] amino]ethoxy]-benzamide methanesulfonate salt
• 1-(2-((3-Carbamoyl-4-hydroxy)phenoxy)ethylamino)-3-(4-(1-methyl-4-trifluoromethyl-2-imidazolyl)phenoxy)-2-propanoldihyd
• 2-Hydroxy-5-(2-((2-hydroxy-3-(4-(1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl)phenoxy)propyl)amino)ethoxy)benzamide methanesulfonate
• 2-Hydroxy-5-[2-[[2-hydroxy-3-[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenoxy]propyl]amino]ethoxy]benzamide methanesulfonate (1:1)
• Benzamide, 2-hydroxy-5-[2-[[2-hydroxy-3-[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenoxy]propyl]amino]ethoxy]-, methanesulfonate (1:1)
• Benzamide, 2-hydroxy-5-[2-[[2-hydroxy-3-[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenoxy]propyl]amino]ethoxy]-, monomethanesulfonate (salt)
• CGP 20712 mesylate
• CGP-20712A methanesulfonate salt
• CGP207122HCl
• Cgp 20712 Dihydrochloride
• Cgp 20712A

CGP 20712 A

CAS: 105737-62-0

CGP 20712 A

Purity: ≥98%

Molecular weight: 590.57g/mol

Ref: 54-BUP14361

CGP 20712 A

CAS: 105737-62-0

CGP 20712 A (CGP 20712 mesylate) is a β1-adrenergic receptor antagonist with antihypertensive activity that reverses RKT-induced gastric relaxation.

Formula: C₂₄H₂₉F₃N₄O₈S

Purity: 99.37%

Color and Shape: Solid

Molecular weight: 590.57

Ref: TM-T10778