CAS 105784-61-0: TEMAFLOXACIN HYDROCHLORIDE

Description: Temafloxacin hydrochloride is a synthetic antibiotic belonging to the fluoroquinolone class, primarily used for its antibacterial properties. It exhibits a broad spectrum of activity against various Gram-positive and Gram-negative bacteria, making it effective in treating a range of infections. The compound is characterized by its ability to inhibit bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication and transcription. Temafloxacin hydrochloride is typically administered orally and is known for its favorable pharmacokinetic profile, including good absorption and distribution in body tissues. Its chemical structure includes a bicyclic core with fluorine substituents, which enhance its potency and stability. However, like other fluoroquinolones, it may be associated with potential side effects, including gastrointestinal disturbances and, in rare cases, tendon damage. Due to safety concerns and the emergence of resistance, its clinical use has become more restricted. Overall, temafloxacin hydrochloride represents an important option in the antibiotic arsenal, particularly for specific bacterial infections.

Formula: C₂₁H₁₉ClF₃N₃O₃

InChI: InChI=1/C21H18F3N3O3.ClH/c1-11-9-26(5-4-25-11)19-8-18-13(7-16(19)24)20(28)14(21(29)30)10-27(18)17-3-2-12(22)6-15(17)23;/h2-3,6-8,10-11,25H,4-5,9H2,1H3,(H,29,30);1H

Synonyms:

• Temafloxacin hydrochloride [USAN]
• (+-)-1-(2,4-Difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, monohydrochloride
• Abbott 62254
• Omniflox
• Temafloxacin HCl
• Unii-Oc5Igj7J6I
• 3-Quinolinecarboxylic acid, 1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, monohydrochloride, (+-)-
• 1-(2,4-Difluorophenyl)-6-Fluoro-7-(3-Methylpiperazin-1-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid Hydrochloride (1:1)
• Temafloxacin hydrochloride

Temafloxacin hydrochloride

CAS: 105784-61-0

• Formula: C₂₁H₁₉ClF₃N₃O₃
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 453.8420695999999

Temafloxacin hydrochloride

CAS: 105784-61-0

Temafloxacin Hydrochloride

CAS: 105784-61-0

• Formula: C₂₁H₁₈F₃N₃O₃·ClH
• Color and Shape: Neat
• Molecular weight: 453.842

Temafloxacin hydrochloride

CAS: 105784-61-0

• Purity: 95.0%
• Molecular weight: 453.8500061035156

1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4

CAS: 105784-61-0

1-(2,4-Difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4 (DFFPPM) is a synthetic compound that belongs to the class of antimicrobial agents. It …

• Formula: C₂₁H₁₉ClF₃N₃O₃
• Purity: Min. 95%
• Molecular weight: 453.84 g/mol