CAS 105816-04-4

Nateglinide

Description:

Nateglinide is an oral hypoglycemic agent primarily used in the management of type 2 diabetes mellitus. It belongs to the class of medications known as meglitinides, which stimulate insulin secretion from the pancreas in response to meals, thereby helping to control postprandial blood glucose levels. The chemical formula of nateglinide is C19H28N2O4S, and it features a unique structure that includes a sulfonamide group, which is integral to its mechanism of action. Nateglinide is characterized by its rapid onset and short duration of action, making it particularly effective for controlling blood sugar spikes after meals. It is typically administered shortly before meals and is often used in conjunction with other antidiabetic medications. Common side effects may include hypoglycemia, gastrointestinal disturbances, and weight gain. As with any medication, it is essential for patients to consult healthcare professionals for personalized advice and monitoring while using nateglinide.

Formula: C₁₉H₂₇NO₃

InChI: InChI=1S/C19H27NO3/c1-13(2)15-8-10-16(11-9-15)18(21)20-17(19(22)23)12-14-6-4-3-5-7-14/h3-7,13,15-17H,8-12H2,1-2H3,(H,20,21)(H,22,23)/t15-,16-,17-/m1/s1

InChI key: InChIKey=OELFLUMRDSZNSF-BRWVUGGUSA-N

SMILES: C(N[C@H](CC1=CC=CC=C1)C(O)=O)(=O)[C@H]2CC[C@H](C(C)C)CC2

Synonyms:

• AY 4166
• N-[[trans-4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine
• D-Phenylalanine, N-[[trans-4-(1-methylethyl)cyclohexyl]carbonyl]-
• D-Phenylalanine, N-[[4-(1-methylethyl)cyclohexyl]carbonyl]-, trans-
• A 4166

Nateglinide

CAS: 105816-04-4

Formula: C₁₉H₂₇NO₃

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 317.43

Ref: 3B-N0912

NATEGLINIDE CRS

CAS: 105816-04-4

NATEGLINIDE CRS

Formula: C₁₉H₂₇NO₃

Color and Shape: White. Powder.

Molecular weight: 317.4226

Ref: 41-Y0001437

Nateglinide

CAS: 105816-04-4

Aromatic cyclic amides (including cyclic carbamates) an

Formula: C₁₉H₂₇NO₃

Color and Shape: White Powder

Molecular weight: 317.19909

Ref: 45-1457607

(2R)-3-phenyl-2-{[(1r,4r)-4-(propan-2-yl)cyclohexyl]formamido}propanoic acid

CAS: 105816-04-4

Formula: C₁₉H₂₇NO₃

Purity: 99%

Color and Shape: Solid

Molecular weight: 317.4226

Ref: IN-DA003SQL

Nateglinide

CAS: 105816-04-4

Nateglinide

Purity: ≥98%

Molecular weight: 317.42g/mol

Ref: 54-BUP14078

Nateglinide

CAS: 105816-04-4

Nateglinide

Purity: 99%

Molecular weight: 317.42g/mol

Ref: 54-OR1028770

Nateglinide

CAS: 105816-04-4

Formula: C₁₉H₂₇NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 317.43

Ref: 4Z-N-023

Nateglinide

CAS: 105816-04-4

Formula: C₁₉H₂₇NO₃

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 317.42

Ref: 7W-GP5047

Nateglinide

CAS: 105816-04-4

Formula: C₁₉H₂₇NO₃

Color and Shape: Neat

Molecular weight: 317.42

Ref: 04-C15499000

Nateglinide

Controlled Product

CAS: 105816-04-4

Formula: C₁₉H₂₇NO₃

Color and Shape: White To Off-White

Molecular weight: 317.42

Ref: 86-MM0847.00

Nateglinide

CAS: 105816-04-4

Nateglinide is an oral drug for type 2 diabetes, stimulating insulin release; may cause rare acute liver injury.

Formula: C₁₉H₂₇NO₃

Purity: 99.93% - 99.94%

Color and Shape: White Crystalline Powder

Molecular weight: 317.42

Ref: TM-T1674

Nateglinide RS

CAS: 105816-04-4

Color and Shape: White Solid Crystalline Powder

Ref: 2K-1100500021

Nateglinide

Controlled Product

CAS: 105816-04-4

Applications An amino-acid derivative that stimulates insulin secretion. Used as an antidiabetic.
References Shinkai, H., et al.: J. Med. Chem., 32, 1436 (1989), Sato, Y., et al.: Diabetes Res. Clin. Pract., 12, 53 (1991), Vicent, D., et al.: J. Clin. Invest., 111, 1373 (2003), Ceriello, A., et al.: Diabet. Med., 21, 171 (2004),

Formula: C₁₉H₂₇NO₃

Color and Shape: White To Off-White

Molecular weight: 317.42

Ref: TR-N379375

Nateglinide

CAS: 105816-04-4

Nateglinide is used to treat type 2 diabetes mellitus as an oral hypoglycemic, insulinotropic agent. It is a blocker of ATP-dependent potassium channels and works by increasing the body's production of insulin, which lowers blood glucose levels. Nateglinide has been shown to be effective in reducing postprandial blood glucose levels in patients with type 2 diabetes who have not responded well to other treatments. The effects of nateglinide are reversible.

Formula: C₁₉H₂₇NO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 317.42 g/mol

Ref: 3D-FN26165

Nateglinide - Bio-X ™

CAS: 105816-04-4

Nateglinide is used to treat type 2 diabetes mellitus as an oral hypoglycemic, insulinotropic agent. It is a blocker of ATP-dependent potassium channels and works by increasing the body's production of insulin, which lowers blood glucose levels. Nateglinide has been shown to be effective in reducing postprandial blood glucose levels in patients with type 2 diabetes who have not responded well to other treatments. The effects of nateglinide are reversible.

Formula: C₁₉H₂₇NO₃

Purity: Min. 95%

Molecular weight: 317.42 g/mol

Ref: 3D-FE22688

Nateglinide

CAS: 105816-04-4

Purity: 99%

Molecular weight: 317.429

Ref: 10-F979686