CAS 105826-92-4: tropisetron hydrochloride
Description:Tropisetron hydrochloride is a chemical compound primarily used as an antiemetic, particularly in the prevention of nausea and vomiting associated with chemotherapy and surgery. It belongs to the class of serotonin 5-HT3 receptor antagonists, which function by blocking the action of serotonin at these receptors in the central nervous system and gastrointestinal tract. This action helps to mitigate the sensations of nausea and vomiting. The compound is typically presented as a white to off-white crystalline powder, soluble in water and methanol, which facilitates its formulation in various pharmaceutical preparations. Its molecular structure includes a piperidine ring, contributing to its pharmacological activity. Tropisetron hydrochloride is administered orally or intravenously, depending on the clinical scenario, and is generally well-tolerated, although side effects may include headache, constipation, or dizziness. As with any medication, it is essential to use it under medical supervision to ensure safety and efficacy.
Formula:C17H21ClN2O2
InChI:InChI=1/C17H20N2O2.ClH/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16;/h2-5,10-13,18H,6-9H2,1H3;1H/t11-,12+,13+;
InChI key:InChIKey=XIEGSJAEZIGKSA-LUNMCBQDNA-N
SMILES:Cl.O=C(OC1CC2N(C)C(CC2)C1)C3=CNC=4C=CC=CC43
- Synonyms:
- (1R,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate hydrochloride (1:1)
- 1H-Indole-3-carboxylic acid, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrochloride (1:1)
- 1H-Indole-3-carboxylic acid, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, monohydrochloride
- 1H-Indole-3-carboxylic acid, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, monohydrochloride, endo-
- 8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate hydrochloride (1:1)
- Novaban
- Sdz-Ics 930
- Tropiserton Hydrochloride
- Tropisetron HCl
