CAS 105827-91-6

2-Chloro-5-(chloromethyl)thiazole

Description:

2-Chloro-5-(chloromethyl)thiazole is a heterocyclic organic compound characterized by the presence of a thiazole ring, which is a five-membered ring containing both sulfur and nitrogen atoms. This compound features two chlorine substituents: one at the second position and another chloromethyl group at the fifth position of the thiazole ring. It is typically a colorless to pale yellow liquid or solid, depending on its physical state at room temperature. The presence of chlorine atoms contributes to its reactivity, making it useful in various chemical syntheses and applications, particularly in the pharmaceutical and agrochemical industries. The compound may exhibit biological activity, which can be of interest in drug development. Additionally, it is important to handle this substance with care due to potential toxicity and environmental impact. Proper safety measures should be observed when working with this compound in laboratory settings.

Formula: C₄H₃Cl₂NS

InChI: InChI=1S/C4H3Cl2NS/c5-1-3-2-7-4(6)8-3/h2H,1H2

InChI key: InChIKey=VRMUIVKEHJSADG-UHFFFAOYSA-N

SMILES: C(Cl)C=1SC(Cl)=NC1

Synonyms:

• 2-Chloro-5-(Chloromethyl)-1,3-Thiazole
• 2-Chloro-5-Chloromethyl-Thiazole
• 2-Chloro-5-chloro methylthiazole
• 2-Chloro-5-thiazolylmethyl chloride
• 5-Chloromethyl-2-chloro-1,3-thiazole
• CCT
• Thiazole, 2-chloro-5-(chloromethyl)-

2-Chloro-5-(chloromethyl)thiazole

CAS: 105827-91-6

Formula: C₄H₃Cl₂NS

Purity: >98.0%(GC)

Color and Shape: White to Light yellow powder to lump

Molecular weight: 168.04

Ref: 3B-C3295

2-Chloro-5-chloromethylthiazole

CAS: 105827-91-6

Formula: C₄H₃Cl₂NS

Purity: 95%

Color and Shape: Liquid

Molecular weight: 168.0443

Ref: IN-DA003388

2-Chloro-5-(chloromethyl)-1,3-thiazole

CAS: 105827-91-6

2-Chloro-5-(chloromethyl)-1,3-thiazole

Formula: C₄H₃Cl₂NS

Purity: ≥95%

Color and Shape: orange. low melting solid

Molecular weight: 168.04g/mol

Ref: 54-OR4254

2-Chloro-5-chloromethylthiazole

CAS: 105827-91-6

Ref: 7W-GK8517

2-Chloro-5-(chloromethyl)thiazole

Controlled Product

CAS: 105827-91-6

Applications 2-Chloro-5-(chloromethyl)thiazole is a useful synthetic intermediate used in the synthesis of Ritonavir (R535000); a second generation anti-AIDS drug and a selective HIV protease inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Meng, F., et al.: Guangzhou Huagong, 40, 66 (2012); Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994); Ammaranond, P., et al.: J. Clin. Virol., 26, 153 (2003); Harrigan, P., et al.: J. Infect. Dis., 191, 339 (2005); Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788 (2006)

Formula: C₄H₃Cl₂NS

Color and Shape: Neat

Molecular weight: 168.04

Ref: TR-C367145

2-Chloro-5-chloromethylthiazole

CAS: 105827-91-6

Formula: C₄H₃Cl₂NS

Purity: 95%

Color and Shape: Solid, Liquid

Molecular weight: 168.04

Ref: 10-F016115

2-Chloro-5-chloromethylthiazole

CAS: 105827-91-6

2-Chloro-5-chloromethylthiazole is an aliphatic hydrocarbon that has been used to chlorinate a variety of organic compounds. It reacts with hydrochloric acid and chlorine at low energy, producing chloride in the process. This chemical can be synthesized by reacting n-dimethyl formamide with hydrogen chloride. 2-Chloro-5-chloromethylthiazole can also be used as a crosslinking agent to react with the amine groups on proteins.

Purity: Min. 95%

Ref: 3D-FC38617