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CAS 105851-17-0

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Fludeoxyglucose F 18

Description:
Fludeoxyglucose F-18, commonly referred to as FDG, is a radiopharmaceutical used primarily in positron emission tomography (PET) imaging. It is a glucose analog where the hydroxyl group at the 2-position is replaced by a fluorine-18 isotope, making it a useful tracer for metabolic activity in tissues. FDG is characterized by its ability to mimic glucose, allowing it to be taken up by cells, particularly those with high metabolic rates, such as cancer cells. The compound is typically produced through a cyclotron and has a short half-life, necessitating its use shortly after synthesis. Its chemical formula is C₁₈H₁₉F₁₈O₆, and it is soluble in water, which facilitates its administration in clinical settings. The uptake of FDG in tissues can provide valuable information regarding tumor presence, progression, and response to therapy, making it an essential tool in oncology. Safety and efficacy are well-established, with regulatory approvals in place for its clinical use.
Formula:C6H11FO5
InChI:InChI=1/C6H11FO5/c7-3-5(10)4(9)2(1-8)12-6(3)11/h2-6,8-11H,1H2/t2-,3-,4-,5-,6+/m1/s1/i7-1
InChI key:InChIKey=ZCXUVYAZINUVJD-AHXZWLDOSA-N
SMILES:C(O)[C@@H]1[C@@H](O)[C@H](O)[C@@H]([18F])[C@@H](O)O1
Synonyms:
  • (2S,3R,4S,5R,6R)-3-fluoro-6-(hydroxymethyl)oxane-2,4,5-triol
  • 2-(Fluoro-18F)-2-deoxy-alpha-glucopyranose
  • 2-Deoxy-2-(fluoro-<sup>18</sup>F)-α-<span class="text-smallcaps">D</span>-glucopyranose
  • 2-deoxy-2-(~18~F)fluoro-alpha-D-glucopyranose
  • 2-deoxy-2-fluoro-alpha-D-glucopyranose
  • Fludeoxyglucose (<sup>18</sup>F)
  • Fluorine F 18 Fluorodeoxyglucose
  • Fluorodeoxyglucose F 18
  • α-<span class="text-smallcaps">D</span>-Glucopyranose, 2-deoxy-2-(fluoro-<sup>18</sup>F)-
  • 2-Deoxy-2-(fluoro-18F)-α-D-glucopyranose
  • See more synonyms
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