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CAS 105889-45-0

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Cefcapene pivoxil

Description:
Cefcapene pivoxil is a broad-spectrum cephalosporin antibiotic, primarily used for the treatment of various bacterial infections. It is characterized by its ability to inhibit bacterial cell wall synthesis, making it effective against both Gram-positive and Gram-negative bacteria. The compound is a prodrug, which means it is converted into its active form, cefcapene, after administration. Cefcapene pivoxil is known for its oral bioavailability, allowing for convenient administration compared to other antibiotics that may require intravenous delivery. The substance exhibits stability in the presence of certain beta-lactamases, which are enzymes produced by some bacteria to resist antibiotic action. Its pharmacokinetic profile includes a relatively short half-life, necessitating multiple doses for sustained therapeutic effects. Additionally, cefcapene pivoxil is generally well-tolerated, although potential side effects may include gastrointestinal disturbances and allergic reactions. As with all antibiotics, appropriate use is crucial to minimize the risk of developing antibiotic resistance.
Formula:C23H29N5O8S2
InChI:InChI=1/C23H29N5O8S2/c1-5-6-12(13-9-38-21(24)26-13)16(29)27-14-17(30)28-15(11(7-34-22(25)33)8-37-18(14)28)19(31)35-10-36-20(32)23(2,3)4/h6,9,14,18H,5,7-8,10H2,1-4H3,(H2,24,26)(H2,25,33)(H,27,29)/b12-6+/t14-,18-/m1/s1
Synonyms:
  • (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, (2,2-Dimethyl-1-oxopropoxy)methyl Ester
  • Fumax
  • S-1108
  • Cefcapene Piroxil
  • Flumax
  • Cefcapene Pivoxil & its intermediates(R&D)
  • [(2,2-dimethylpropanoyl)oxy]methyl (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino}-3-[(carbamoyloxy)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • [(2,2-dimethylpropanoyl)oxy]methyl (6R,7R)-7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino}-3-[(carbamoyloxy)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • See C242555
  • Cefcapene Pivoxil
  • See more synonyms
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