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CAS 105931-58-6

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5'-O-(4,4'-DIMETHOXYTRITYL)-N6-METHYL-2'-DEOXYADENOSINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE

Description:
5'-O-(4,4'-Dimethoxytrityl)-N6-methyl-2'-deoxyadenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite is a specialized chemical compound primarily used in the field of nucleic acid synthesis, particularly for the solid-phase synthesis of oligonucleotides. This compound features a modified adenosine structure, which includes a dimethoxytrityl (DMT) protecting group at the 5' position, enhancing its stability and facilitating the synthesis process. The N6-methyl substitution provides additional steric hindrance, which can influence the compound's reactivity and binding properties. The 3'-phosphoramidite moiety, characterized by the presence of a cyanoethyl group and diisopropylamine, is crucial for the coupling reactions during oligonucleotide synthesis, allowing for the formation of phosphodiester bonds. This compound is typically utilized in automated synthesizers, enabling the efficient production of custom DNA or RNA sequences for research, therapeutic, or diagnostic applications. Its unique structural features contribute to its effectiveness in facilitating precise nucleotide incorporation during synthesis.
Formula:C41H50N7O5P
Synonyms:
  • N6-Methyl-Da Cep
  • N6-Methyl-5'-O-DMT-2'-deoxyadenosine-3'-CE-Phosphoramidite
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