CAS 105942-09-4

2-Fluoro-4-cyanobenzyl bromide

Description:

2-Fluoro-4-cyanobenzyl bromide is an organic compound characterized by its aromatic structure, which includes a benzene ring substituted with a fluorine atom, a cyano group, and a bromomethyl group. The presence of the fluorine atom typically enhances the compound's reactivity and lipophilicity, while the cyano group contributes to its electronic properties, making it a useful intermediate in organic synthesis. The bromide moiety serves as a good leaving group, facilitating nucleophilic substitution reactions. This compound is often utilized in the synthesis of pharmaceuticals and agrochemicals due to its ability to participate in various chemical transformations. Additionally, its unique combination of functional groups may impart specific biological activities, making it of interest in medicinal chemistry. As with many halogenated compounds, safety precautions should be taken when handling 2-Fluoro-4-cyanobenzyl bromide, as it may pose health risks and environmental concerns. Proper storage and disposal methods are essential to mitigate any potential hazards associated with its use.

Formula: C₈H₅BrFN

InChI: InChI=1/C8H4FNO/c9-8-3-6(4-10)1-2-7(8)5-11/h1-3,5H

SMILES: c1cc(C=O)c(cc1C#N)F

Synonyms:

• 4-Cyano-2-Fluorobenzyl Bromide
• 2-Fluoro-4-Cyano-Benzylbromide
• Benzonitrile, 4-(Bromomethyl)-3-Fluoro-
• 4-Cyano-2-fluorobenzylbromide97%
• 4-Cyano-2-fluorbenzylbromid
• 3-Fluoro-4-Formylbenzonitrile
• 2-Fluoro-4-Cyanbenzyl Bromide
• 4-(Bromomethyl)-3-Fluorobenzonitrile
• 2-Fluoro-4-Cyanobenzylbromide

4-Bromomethyl-3-fluorobenzonitrile, 95%

CAS: 105942-09-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₅BrFN

Purity: 95%

Molecular weight: 214.04

Ref: 02-H63245

4-(BroMoMethyl)-3-fluorobenzonitrile

CAS: 105942-09-4

Formula: C₈H₅BrFN

Purity: 97%

Color and Shape: Solid

Molecular weight: 214.0344

Ref: IN-DA003H9C

4-(Bromomethyl)-3-fluorobenzonitrile

CAS: 105942-09-4

4-(Bromomethyl)-3-fluorobenzonitrile

Formula: C₈H₅BrFN

Purity: 97%

Color and Shape: off-white to faint yellow crystalline solid

Molecular weight: 214.03g/mol

Ref: 54-PC9915

4-(Bromomethyl)-3-fluorobenzonitrile

CAS: 105942-09-4

Formula: C₈H₅BrFN

Purity: >98.0%(GC)

Color and Shape: White to Yellow to Orange powder to crystal

Molecular weight: 214.04

Ref: 3B-B3204

4-Cyano-2-fluorobenzyl bromide

CAS: 105942-09-4

Formula: C₈H₅BrFN

Purity: 97%

Color and Shape: Solid

Molecular weight: 214.037

Ref: 10-F032722

4-Cyano-2-fluorobenzyl bromide

CAS: 105942-09-4

4-Cyano-2-fluorobenzyl bromide is a methyl ester that can be used as a reagent for the synthesis of chiral α-amino acids. It can also be used as an enantioselective methylating agent for the synthesis of γ-secretase inhibitors. The methodology for the convergent synthesis of this compound includes alkylation with glycine followed by an enantioselective hydrolysis, which results in optically pure 4-cyano-2-fluorobenzyl bromide.

Formula: C₈H₅BrFN

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 214.03 g/mol

Ref: 3D-FC36769