CAS 105956-99-8

Clinafloxacin hydrochloride

Description:

Clinafloxacin hydrochloride is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily effective against a variety of Gram-positive and Gram-negative bacteria, making it useful in treating various infections. The compound features a bicyclic core structure typical of fluoroquinolones, which includes a fluorine atom that enhances its antimicrobial potency. Clinafloxacin hydrochloride is soluble in water, which facilitates its administration in clinical settings. Its mechanism of action involves the inhibition of bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and repair. This antibiotic is often utilized in the treatment of respiratory and urinary tract infections, as well as skin and soft tissue infections. However, like other fluoroquinolones, it may be associated with potential side effects, including gastrointestinal disturbances and, in rare cases, tendon damage. As with any antibiotic, appropriate use is essential to mitigate the risk of developing antibiotic resistance.

Formula: C₁₇H₁₈Cl₂FN₃O₃

InChI: InChI=1/C17H17ClFN3O3.ClH/c18-13-14-10(5-12(19)15(13)21-4-3-8(20)6-21)16(23)11(17(24)25)7-22(14)9-1-2-9;/h5,7-9H,1-4,6,20H2,(H,24,25);1H

InChI key: InChIKey=BMACYHMTJHBPOX-UHFFFAOYSA-N

SMILES: ClC1=C2N(C=C(C(O)=O)C(=O)C2=CC(F)=C1N3CC(N)CC3)C4CC4.Cl

Synonyms:

• 3-Quinolinecarboxylic acid, 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, hydrochloride (1:1)
• 3-Quinolinecarboxylic acid, 7-(3-amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, monohydrochloride
• 7-(3-Amino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid hydrochloride
• Am 1091
• Ci 960
• Clinafloxacin Hcl
• Clinafloxacinhydrochloride
• Clinanfloxacin Hydrochloride
• Kr 11095
• ClinafoxacinHCl
• 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid hydrochloride
• 7-(3-azanylpyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-quinoline-3-carboxylic acid hydrochloride
• HYDROGEN CLINAFLOXACIN CHLORIDE
• 3-Quinolinecarboxylic acid, 7-(3-aMino-1-pyrrolidinyl)-8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, Monohydrochloride (9CI)
• M 1091
• Clinafloxacin hydrochloride USP/EP/BP
• 7-(3-aminopyrrolidin-1-yl)-8-chloro-1-cyclopropyl-6-fluoro-4-keto-quinoline-3-carboxylic acid hydrochloride

Clinafloxacin Hydrochloride

CAS: 105956-99-8

Formula: C₁₇H₁₈Cl₂FN₃O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 402.2475

Ref: IN-DA008TUO

Clinafloxacin hydrochloride

CAS: 105956-99-8

Formula: C₁₇H₁₇ClFN₃O₃

Purity: ≥ 95.0%

Color and Shape: White to pale yellow powder

Molecular weight: 365.79

Ref: 7W-GP2799

Clinafloxacin Hydrochloride

Controlled Product

CAS: 105956-99-8

Stability Hygroscopic
Applications A new fluoroquinolone antimicrobial agent as a potent intraphagocytic bactericidal agent for both gram-positive and gram-negative bacteria.
References Phillips, G., et al.: J. Antimicrob. Chemother., 26, 783 (1990), Robertson, D., et al.: Toxicol. Appl. Pharmacol., 111, 221 (1991), Torniainen, K., et al.: J. Pharm. Biomed. Anal., 15, 887 (1997),

Formula: C₁₇H₁₇ClFN₃O₃·ClH

Color and Shape: Neat

Molecular weight: 402.25

Ref: TR-C579000

Clinafloxacin HCl

CAS: 105956-99-8

Inhibits bacterial regulatory enzyme DNA gyrase

Formula: C₁₇H₁₇ClFN₃O₃·HCl

Purity: Min. 95 Area-%

Color and Shape: Solid

Molecular weight: 402.25 g/mol

Ref: 3D-AC64984