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Clodronate

CAS 10596-23-3: Clodronate

Description:Clodronate is a bisphosphonate compound primarily used in the treatment of bone disorders, particularly in conditions such as osteoporosis and metastatic bone disease. It functions by inhibiting osteoclast-mediated bone resorption, thereby helping to maintain bone density and strength. Clodronate is characterized by its ability to bind to hydroxyapatite in bone tissue, which enhances its therapeutic effects. The chemical structure of clodronate includes two phosphonate groups, contributing to its high affinity for bone mineral. It is typically administered orally or intravenously, depending on the clinical context. Clodronate is known for its relatively low toxicity profile compared to other bisphosphonates, although it can still cause side effects such as gastrointestinal disturbances and, in rare cases, osteonecrosis of the jaw. Its pharmacokinetics involve rapid absorption and distribution, with a significant portion being retained in the bone. Overall, clodronate plays a crucial role in managing bone-related diseases, offering a therapeutic option for patients at risk of skeletal complications.

Formula:CH4Cl2O6P2

InChI:InChI=1S/CH4Cl2O6P2/c2-1(3,10(4,5)6)11(7,8)9/h(H2,4,5,6)(H2,7,8,9)

InChI key:InChIKey=ACSIXWWBWUQEHA-UHFFFAOYSA-N

SMILES:O=P(O)(O)C(Cl)(Cl)P(=O)(O)O

  • Synonyms:
  • (Dichloromethanediyl)Bis(Phosphonic Acid)
  • (Dichloromethylene)bis(phosphonic acid)
  • 10596-23-3
  • Acide Clodronique
  • Acido Clodronico
  • Cl 2MDP
  • Clastoban
  • Clodrolip
  • Clodronate
  • Clodroninsaure
  • See more synonyms
  • Clodrosome
  • DMDP derivative
  • Dichloromethylenebisphosphonic Acid
  • Dichloromethylenediphosphonic acid
  • Dmdp
  • Lodronate
  • Methanedichlorodiphosphonic acid
  • P,P′-(Dichloromethylene)bis[phosphonic acid]
  • Phosphonic acid, (dichloromethylene)bis-
  • Phosphonic acid, (dichloromethylene)di-
  • Phosphonic acid, P,P'-(dichloromethylene)bis-
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Found 4 products.

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Ref: IN-DA0039PT

5mg114.00 €
25mg155.00 €
100mg219.00 €
250mg579.00 €
500mg613.00 €
Estimated delivery in United States, on Thursday 6 Mar 2025
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Ref: 4Z-C-219001

5mgTo inquire
10mgTo inquire
25mgTo inquire
50mgTo inquire
100mgTo inquire
Estimated delivery in United States, on Friday 7 Mar 2025
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Clodronic Acid

Controlled Product
CAS:10596-23-3

Ref: TR-C583530

1mg312.00 €
10mg2,066.00 €
Estimated delivery in United States, on Tuesday 18 Mar 2025
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(dichloromethylene)bis(phosphonic acid)

CAS:10596-23-3

Ref: 3D-KAA59623

10g348.00 €
25g451.00 €
50g615.00 €
100g905.00 €
Estimated delivery in United States, on Friday 2 May 2025
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