CAS 106-45-6

4-Methylbenzenethiol

Description:

4-Methylbenzenethiol, also known as p-cresol thiol or para-methylbenzenethiol, is an organic compound characterized by a thiol functional group (-SH) attached to a methyl-substituted benzene ring. Its molecular formula is C7H8S, and it features a methyl group at the para position relative to the thiol group on the benzene ring. This compound is typically a colorless to pale yellow liquid with a strong, unpleasant odor reminiscent of garlic or rotten eggs. It is soluble in organic solvents and has limited solubility in water. 4-Methylbenzenethiol is known for its reactivity, particularly in nucleophilic substitution reactions, and can participate in various chemical transformations due to the presence of the thiol group. It is used in organic synthesis and may serve as an intermediate in the production of other chemicals. Additionally, it is important to handle this substance with care due to its potential toxicity and irritant properties.

Formula: C₇H₈S

InChI: InChI=1S/C7H8S/c1-6-2-4-7(8)5-3-6/h2-5,8H,1H3

InChI key: InChIKey=WLHCBQAPPJAULW-UHFFFAOYSA-N

SMILES: CC1=CC=C(S)C=C1

Synonyms:

• 1-Mercapto-4-methylbenzene
• 4-Mercaptotoluene
• 4-Methyl-1-thiophenol
• 4-Methylbenzenethiol
• 4-Methylphenyl mercaptan
• 4-Methylphenylthiol
• 4-Methylthiophenol
• 4-Thiocresol
• 4-Toluenethiol
• Nsc 2227
• Nsc 229565
• Thiophenol, 4-Methyl-
• Toluene-4-Thiol
• Tolueno-4-Tiol
• Toluol-4-thiol
• p-Mercaptotoluene
• p-Methylbenzenethiol
• p-Methylbenzenthiol
• p-Methylphenyl mercaptan
• p-Methylphenylthiol
• p-Methylthiophenol
• p-Thiocresol
• p-Thiolcresol
• p-Toluenethiol
• p-Tolyl mercaptan
• p-Tolylthiol

p-Thiocresol, 98%

CAS: 106-45-6

p-Thiocresol is used as a pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not

Formula: C₇H₈S

Purity: 98%

Color and Shape: White to yellow, Crystals or powder or crystalline powder or fused/lumpy solid

Molecular weight: 124.20

Ref: 02-B24970

4-Methylthiophenol

CAS: 106-45-6

4-Methylthiophenol

Formula: C₇H₈S

Purity: 98%

Color and Shape: colourless to off white. crystalline solid

Molecular weight: 124.20342g/mol

Ref: 54-OR43548

4-Methylthiophenol

CAS: 106-45-6

Formula: C₇H₈S

Purity: 98.0%

Color and Shape: Solid, Crystalline Powder or Lumps

Molecular weight: 124.2

Ref: 10-F019192

p-Toluenethiol

CAS: 106-45-6

Formula: C₇H₈S

Purity: >97.0%(GC)(T)

Color and Shape: White to Almost white powder to lump

Molecular weight: 124.20

Ref: 3B-T0290

4-Methylbenzenethiol

CAS: 106-45-6

Formula: C₇H₈S

Molecular weight: 124.20

Ref: 4Z-B-139065

4-Methylthiophenol

CAS: 106-45-6

4-Methylthiophenol is a colorless liquid that is soluble in water. It has a molecular weight of 98.12 and an empirical formula of C6H7O2S. 4-Methylthiophenol is used as an analytical reagent, solvent, and chemical intermediate. It exhibits hydrogen bonding interactions with sodium carbonate and trifluoroacetic acid and forms a salt with sodium carbonate. The molecule's stability increases when it interacts with amines and the presence of nucleophiles such as water or alcohols. 4-Methylthiophenol has been shown to be effective at enhancing the fluorescence signal emitted by amines, which makes it useful for laser ablation mass spectrometry (LA-MS). 4-Methylthiophenol can also be used for kinetic energy measurements using FTIR spectroscopy because it will absorb infrared light at 1680 cm−1 from the CO2 laser beam.

Formula: C₇H₈S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 124.2 g/mol

Ref: 3D-FM42992

4-Methylbenzenethiol

Controlled Product

CAS: 106-45-6

Stability Smelly, Air Sensitive
Applications 4-Methylbenzenethiol is used as a reactant in the preparation of sulfides by palladium-catalyzed coupling with aryl halides or sulfonates in presence of Josiphos ligand.
References Fernandez-Rodriguez, M., et al.: J. Am. Chem. Soc., 128, 2180 (2006);

Formula: C₇H₈S

Color and Shape: Neat

Molecular weight: 124.2

Ref: TR-M290510