CAS 106017-08-7: Rufloxacin hydrochloride

Description: Rufloxacin hydrochloride is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily used to treat various bacterial infections, particularly those caused by Gram-negative and some Gram-positive organisms. The compound exhibits a mechanism of action that involves the inhibition of bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. Rufloxacin hydrochloride is typically administered orally and is known for its favorable pharmacokinetic properties, including good absorption and distribution in body tissues. The substance is generally well-tolerated, although potential side effects may include gastrointestinal disturbances, central nervous system effects, and, in rare cases, tendon damage. Its chemical structure features a bicyclic core with a fluorine atom, contributing to its potency and resistance to certain bacterial efflux mechanisms. As with other antibiotics, appropriate use is essential to minimize the risk of developing antibiotic resistance. Rufloxacin hydrochloride is classified under the World Health Organization's list of essential medicines, highlighting its importance in treating infectious diseases.

Formula: C₁₇H₁₈FN₃O₃S·ClH

InChI: InChI=1S/C17H18FN3O3S.ClH/c1-19-2-4-20(5-3-19)14-12(18)8-10-13-16(14)25-7-6-21(13)9-11(15(10)22)17(23)24;/h8-9H,2-7H2,1H3,(H,23,24);1H

InChI key: InChIKey=LPQOADBMXVRBNX-UHFFFAOYSA-N

SMILES: Cl.O=C(O)C1=CN2C3=C(SCC2)C(=C(F)C=C3C1=O)N4CCN(C)CC4

Synonyms:

• 2,3-Dihydro-9-fluoro-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de][1,4]benzothiazine-6-carboxylic acid hydrochloride
• 7H-Pyrido(1,2,3-De)(1,4)Benzothiazine-6-Carboxylicacid,2,3-Dihydro-9-Fluoro-1
• 7H-Pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-, hydrochloride (1:1)
• 7H-Pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-, monohydrochloride
• Isf 09334
• Mf-934
• Monos
• Rufloxacin HCL
• Tebraxin
• Qari
• Rufloxacin hydrochloride

7H-Pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylicacid, 9-fluoro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-, hydrochloride(1:1)

CAS: 106017-08-7

• Formula: C₁₇H₁₉ClFN₃O₃S
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 399.8675

Rufloxacin hydrochloride

CAS: 106017-08-7

• Purity: 99.55%
• Molecular weight: 399.867g/mol

Rufloxacin HCl

CAS: 106017-08-7

• Formula: C₁₇H₁₈FN₃O₃S·HCl
• Color and Shape: Pale Yellow Solid
• Molecular weight: 363.41 36.46

Rufloxacin hydrochloride

CAS: 106017-08-7

• Formula: C₁₇H₁₈FN₃O₃S·HCl
• Purity: ≥ 98.0%
• Color and Shape: Solid
• Molecular weight: 399.87

Rufloxacin hydrochloride

CAS: 106017-08-7

• Formula: C₁₇H₁₈FN₃O₃S·ClH
• Color and Shape: Neat
• Molecular weight: 399.8675

Rufloxacin Hydrochloride

CAS: 106017-08-7

Applications Rufloxacin Hydrochloride inhibits human organic cation transporter 1 (hoCT1) (SLC22A1) but not hOCT2 (SLC22A2), …

• Formula: C₁₇H₁₈FN₃O₃S·ClH
• Color and Shape: Off-White To Light Yellow
• Molecular weight: 399.8675

Rufloxacin HCl

CAS: 106017-08-7

Fluoroquinolone; gyrase inhibitor

• Formula: C₁₇H₁₈FN₃O₃S·HCl
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 399.87 g/mol

Rufloxacin hydrochloride

CAS: 106017-08-7

Rufloxacin HCl (MF-934 HCl): a fluoroquinolone that inhibits topoisomerase and B-cell differentiation.

• Formula: C₁₇H₁₉ClFN₃O₃S
• Purity: 99.55%
• Color and Shape: Solid
• Molecular weight: 399.867