CAS 106017-08-7
:Rufloxacin hydrochloride
Description:
Rufloxacin hydrochloride is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily used to treat various bacterial infections, particularly those caused by Gram-negative and some Gram-positive organisms. The compound exhibits a mechanism of action that involves the inhibition of bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and transcription. Rufloxacin hydrochloride is typically administered orally and is known for its favorable pharmacokinetic properties, including good absorption and distribution in body tissues. The substance is generally well-tolerated, although potential side effects may include gastrointestinal disturbances, central nervous system effects, and, in rare cases, tendon damage. Its chemical structure features a bicyclic core with a fluorine atom, contributing to its potency and resistance to certain bacterial efflux mechanisms. As with other antibiotics, appropriate use is essential to minimize the risk of developing antibiotic resistance. Rufloxacin hydrochloride is classified under the World Health Organization's list of essential medicines, highlighting its importance in treating infectious diseases.
Formula:C17H19ClFN3O3S
InChI:InChI=1/C17H18FN3O3S.ClH/c1-19-2-4-20(5-3-19)14-12(18)8-10-13-16(14)25-7-6-21(13)9-11(15(10)22)17(23)24;/h8-9H,2-7H2,1H3,(H,23,24);1H
InChI key:InChIKey=LPQOADBMXVRBNX-UHFFFAOYSA-N
SMILES:O=C1C=2C3=C(C(=C(F)C2)N4CCN(C)CC4)SCCN3C=C1C(O)=O.Cl
Synonyms:- 2,3-Dihydro-9-fluoro-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de][1,4]benzothiazine-6-carboxylic acid hydrochloride
- 7H-Pyrido(1,2,3-De)(1,4)Benzothiazine-6-Carboxylicacid,2,3-Dihydro-9-Fluoro-1
- 7H-Pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-, hydrochloride (1:1)
- 7H-Pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-, monohydrochloride
- Isf 09334
- Mf-934
- Monos
- Rufloxacin HCL
- Tebraxin
- Qari
- Rufloxacin hydrochloride
- See more synonyms
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Found 9 products.
7H-Pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylicacid, 9-fluoro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-, hydrochloride(1:1)
CAS:Formula:C17H19ClFN3O3SPurity:95%Color and Shape:SolidMolecular weight:399.8675Rufloxacin HCl
CAS:Formula:C17H18FN3O3S·HClColor and Shape:Pale Yellow SolidMolecular weight:363.41 36.46Rufloxacin hydrochloride
CAS:Formula:C17H18FN3O3S·HClPurity:≥ 98.0%Color and Shape:SolidMolecular weight:399.87Rufloxacin Hydrochloride
CAS:Controlled Product<p>Applications Rufloxacin Hydrochloride inhibits human organic cation transporter 1 (hoCT1) (SLC22A1) but not hOCT2 (SLC22A2), and hOCT3 (SLC22A3) expressed in human embryonic kidney cell.<br>References Mulgaonkar, A., et. al.: Antimicrob. Agents Ch., 57, 2705 (2013)<br></p>Formula:C17H18FN3O3S·ClHColor and Shape:Off-White To Light YellowMolecular weight:399.8675Rufloxacin HCl
CAS:<p>Fluoroquinolone; gyrase inhibitor</p>Formula:C17H18FN3O3S·HClPurity:Min. 95%Color and Shape:PowderMolecular weight:399.87 g/molRufloxacin hydrochloride
CAS:<p>Rufloxacin HCl (MF-934 HCl): a fluoroquinolone that inhibits topoisomerase and B-cell differentiation.</p>Formula:C17H19ClFN3O3SPurity:99.80%Color and Shape:SolidMolecular weight:399.867
![7H-Pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylicacid, 9-fluoro-2,3-dihydro-10-(4-methyl-1-pipera…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA007E8Q.jpg&w=3840&q=75)
