CAS 106021-96-9

interleukin-1B fragment 163-171 human

Description:

Interleukin-1 beta (IL-1β) fragment 163-171 is a peptide derived from the human interleukin-1 beta protein, which plays a crucial role in the immune response and inflammation. This specific fragment consists of a sequence of amino acids that is part of the larger IL-1β molecule, known for its pro-inflammatory properties. The CAS number 106021-96-9 identifies this peptide in chemical databases, facilitating its study and application in research. Characteristically, this fragment is involved in various biological processes, including cell signaling and the modulation of immune responses. It can interact with specific receptors on immune cells, influencing cytokine production and promoting inflammatory pathways. The fragment is often utilized in research settings to investigate the mechanisms of inflammation and immune regulation, as well as potential therapeutic applications in diseases characterized by excessive inflammation. Its stability, solubility, and biological activity are important factors that researchers consider when studying its effects in vitro and in vivo.

Formula: C₃₉H₆₄N₁₂O₁₉

InChI: InChI=1/C39H64N12O19/c1-17(2)31(43)38(68)47-18(6-9-25(41)53)32(62)44-15-27(55)45-19(7-10-28(56)57)33(63)46-20(8-11-29(58)59)34(64)51-24(16-52)37(67)49-22(13-26(42)54)35(65)50-23(14-30(60)61)36(66)48-21(39(69)70)5-3-4-12-40/h17-24,31,52H,3-16,40,43H2,1-2H3,(H2,41,53)(H2,42,54)(H,44,62)(H,45,55)(H,46,63)(H,47,68)(H,48,66)(H,49,67)(H,50,65)(H,51,64)(H,56,57)(H,58,59)(H,60,61)(H,69,70)/t18-,19-,20-,21-,22-,23-,24-,31-/m0/s1

SMILES: CC(C)[C@@H](C(=N[C@@H](CCC(=N)O)C(=NCC(=N[C@@H](CCC(=O)O)C(=N[C@@H](CCC(=O)O)C(=N[C@@H](CO)C(=N[C@@H](CC(=N)O)C(=N[C@@H](CC(=O)O)C(=N[C@@H](CCCCN)C(=O)O)O)O)O)O)O)O)O)O)N

Synonyms:

• Interleukin-1beta (163-171)
• IL-1beta (163-171)
• Interleukin 1-beta (163-171)
• L-Lysine, N2-(N-(N2-(N-(N-(N-(N-(N2-L-valyl-L-glutaminyl)glycyl)-L-alph-glutamyl)-L-alpha-glutamyl)-L-seryl)-L-asparaginyl)-L-alpha-aspartyl)-
• L-valyl-L-glutaminylglycyl-L-alpha-glutamyl-L-alpha-glutamyl-L-seryl-L-asparaginyl-L-alpha-aspartyl-L-lysine
• Val-Gln-Gly-Glu-Glu-Ser-Asn-Asp-Lys

IL-1β (163-171) (human) trifluoroacetate salt

CAS: 106021-96-9

Interleukin-1 beta (IL-1β) is a cytokine that is produced by activated macrophages and T cells. It is an important regulator of immune function, inducing fever, activating the inflammatory response, and increasing vascular permeability. IL-1β is a 163-amino acid polypeptide with a molecular weight of 18.7 kDa. The trifluoroacetate salt of IL-1β has been shown to be active in vitro against human leukemic cells and to have an interferon-gamma activity in vitro.

Formula: C₃₉H₆₄N₁₂O₁₉

Purity: Min. 95%

Molecular weight: 1,004.99 g/mol

Ref: 3D-FI109999