CAS 10605-02-4

Palmatine chloride

Description:

Palmatine chloride, with the CAS number 10605-02-4, is a quaternary ammonium salt derived from palmatine, a natural alkaloid found in various plant species. This compound typically appears as a white to off-white crystalline solid and is known for its solubility in water and organic solvents. Palmatine chloride exhibits antimicrobial properties, making it of interest in pharmaceutical and cosmetic applications. Its structure features a long hydrocarbon chain, which contributes to its surfactant properties, allowing it to interact with biological membranes. Additionally, palmatine chloride may have potential therapeutic effects, including anti-inflammatory and antioxidant activities. However, like many quaternary ammonium compounds, it should be handled with care due to potential toxicity and irritant effects on skin and mucous membranes. Overall, palmatine chloride is a versatile compound with applications in various fields, including medicine, agriculture, and materials science, warranting further research into its properties and potential uses.

Formula: C₂₁H₂₃NO₄

InChI: InChI=1/C21H23NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,9-12,17H,7-8H2,1-4H3

SMILES: COc1ccc2=CC3c4cc(c(cc4CCN3C=c2c1OC)OC)OC

Synonyms:

• 2,3,9,10-Tetramethoxyprotoberberinchloride
• Berbericine Chloride
• Palmatine Hydrochloride
• Palmatine HCL
• 2,3,9,10-Tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium chloride
• 2,3,9,10-Tetramethoxy-5,6-Dihydroisoquino[3,2-A]Isoquinolinium Chloride
• 2,3,9,10-tetramethoxy-5,13a-dihydro-6H-isoquino[3,2-a]isoquinoline

Palmatine Chloride

CAS: 10605-02-4

Formula: C₂₁H₂₂ClNO₄

Purity: >97.0%(HPLC)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 387.86

Ref: 3B-P2138

Palmatine chloride

CAS: 10605-02-4

Palmatine chloride analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₂₁H₂₂NO₄Cl

Purity: (HPLC) ≥95%

Color and Shape: Powder

Molecular weight: 387.84

Ref: 11-1688

Palmatine chloride

CAS: 10605-02-4

Palmatine chloride

Formula: C₂₁H₂₂ClNO₄

Purity: 83.7%

Color and Shape: Yellow

Molecular weight: 387.12374

Ref: 47-1165

Palmatine Chloride

CAS: 10605-02-4

Vegetable alkaloids, natural or reproduced by synthesis, their salts and other derivatives, nesoi

Formula: C₂₁H₂₂ClNO₄

Color and Shape: Orange Powder

Molecular weight: 387.12374

Ref: 45-1491900

Dibenzo[a,g]quinolizinium, 5,6-dihydro-2,3,9,10-tetramethoxy-, chloride

CAS: 10605-02-4

Formula: C₂₁H₂₂ClNO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 387.8567

Ref: IN-DA00HAQQ

Palmatine chloride

CAS: 10605-02-4

Palmatine chloride

Purity: ≥95%

Molecular weight: 387.857g/mol

Ref: 54-BUP18653

Palmatine Chloride

CAS: 10605-02-4

Palmatine Chloride

Purity: 97%

Molecular weight: 387.86g/mol

Ref: 54-OR1029972

Palmatine Chloride

CAS: 10605-02-4

Formula: C₂₁H₂₂NO₄·Cl

Molecular weight: 352.41 35.45

Ref: 4Z-B-2220

Palmatine Chloride

CAS: 10605-02-4

Palmatine hydrochloride (PaH), a naturally occurring photosensitizer isolated from traditional Chinese medicine (TCM), can induce remarkable cell apoptosis ,significantly increase intracellular ROS level and significantly kill breast cancer MCF-7 cells; it also has potential in photodynamic therapy on colon adenocarcinoma.[1,2]

Formula: C₂₁H₂₂ClNO₄

Purity: 95%~99%

Color and Shape: White powder

Molecular weight: 387.86

Ref: BP-BP1059

Palmatine chloride

CAS: 10605-02-4

Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.

Formula: C₂₁H₂₂ClNO₄

Purity: 97.9% - 99.47%

Color and Shape: Solid

Molecular weight: 387.857

Ref: TM-T2718

Palmatine chloride

CAS: 10605-02-4

Natural alkaloid

Formula: C₂₁H₂₂NO₄Cl

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 387.86

Ref: 5G-89490

Palmatine Chloride

Controlled Product

CAS: 10605-02-4

Applications Palmatine Chloride is a protoberberine alkaloid, as a potential anti-inflammatory and anti-hypertensive agent.
References Bhadra, K. et al.: Med. Res. Rev., 31, 821 (2011)

Formula: C₂₁H₂₂NO₄·Cl

Color and Shape: Neat

Molecular weight: 387.86

Ref: TR-P144200

Palmatine chloride

CAS: 10605-02-4

Palmatine chloride is an alkaloid that has been isolated from the roots of Corydalis yanhusuo. Palmatine chloride inhibits the activity of toll-like receptor 4, which is a key molecule in inflammation and autoimmunity. This compound also inhibits the synthesis of proinflammatory cytokines such as IL-1β, IL-6, and TNF-α. Palmatine chloride has also been shown to inhibit the production of inflammatory mediators such as nitric oxide (NO) and prostaglandin E2 (PGE2). Furthermore, palmatine chloride has been found to have anti-cancer properties through its inhibition of squamous cell carcinoma cells.

Formula: C₂₁H₂₂NO₄Cl

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 387.86 g/mol

Ref: 3D-FP73849

PALMATINE CHLORIDE

CAS: 10605-02-4

Purity: 97%

Molecular weight: 387.8599854

Ref: 10-F814467