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CAS 106096-93-9

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Fibroblast growth factor 2

Description:
Fibroblast Growth Factor 2 (FGF-2), also known as basic fibroblast growth factor (bFGF), is a member of the fibroblast growth factor family, which plays a crucial role in various biological processes, including cell proliferation, differentiation, and angiogenesis. It is a polypeptide composed of approximately 155 amino acids and is known for its ability to stimulate the growth of fibroblasts and other cell types. FGF-2 is involved in wound healing, tissue repair, and embryonic development. It exhibits a high affinity for heparin and heparan sulfate, which enhances its stability and activity in the extracellular matrix. The substance is typically produced in a recombinant form for research and therapeutic applications. FGF-2 has been studied for its potential in regenerative medicine, particularly in promoting tissue regeneration and repair in various conditions. Its biological activity is modulated by various receptors, primarily the fibroblast growth factor receptors (FGFRs), which are critical for mediating its effects in target cells.
Formula:Unspecified
Synonyms:
  • Astroglial growth factor 2
  • Fibroblast growth factor 2
  • Fibroblast growth factor, basic
  • Basic astroglial growth factor
  • Basic fibroblast growth factor
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