CAS 106224-67-3

NC 182

Description:

NC 182, with the CAS number 106224-67-3, is a chemical compound that belongs to the class of substances known as neuroprotective agents. It is primarily studied for its potential therapeutic applications in neurodegenerative diseases. The compound exhibits properties that may help in protecting neurons from damage and promoting neuronal survival. Its mechanism of action often involves modulation of neurotransmitter systems and reduction of oxidative stress, which are critical factors in neuroprotection. NC 182 is typically characterized by its specific molecular structure, which influences its biological activity and pharmacokinetics. Research into NC 182 has focused on its efficacy, safety profile, and potential side effects, making it a subject of interest in medicinal chemistry and pharmacology. As with many compounds in this category, further studies are necessary to fully understand its therapeutic potential and to establish guidelines for its use in clinical settings.

Formula: C₂₄H₂₄N₄O₅

InChI: InChI=1/C24H24N4O5/c1-28(2)10-9-25-23(30)19-21-20(13-7-5-6-8-14(13)22(19)29)26-17-12-18(32-3)15(24(31)33-4)11-16(17)27-21/h5-8,11-12,27H,9-10H2,1-4H3,(H,25,30)

Synonyms:

• N-beta-Dimethylaminoethyl-9-methoxycarbonyl-5-hydroxy-10-methoxybenzo(a)phenazine-6-carboxamide
• NC-182
• Benzo(a)phenazine-9-carboxylic acid, 6-(((2-(dimethylamino)ethyl)amino)carbonyl)-5-hydroxy-10-methoxy-, methyl ester
• methyl 6-{[2-(dimethylamino)ethyl]carbamoyl}-10-methoxy-5-oxo-5,7-dihydrobenzo[a]phenazine-9-carboxylate

NC182

CAS: 106224-67-3

NC182 is a topo II inhibitor that shows selective and potent topo II inhibition on the induction of topo II-dependent DNA fragmentation.

Formula: C₂₄H₂₄N₄O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 448.47

Ref: TM-T25856