CAS: 1062368-24-4 - 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline

Formula: C₂₅H₂₂N₆

InChI: InChI=1S/C25H22N6/c1-2-4-24-22(3-1)21(9-10-27-24)23-16-29-31-17-19(15-28-25(23)31)18-5-7-20(8-6-18)30-13-11-26-12-14-30/h1-10,15-17,26H,11-14H2

InChI key: InChIKey=CDOVNWNANFFLFJ-UHFFFAOYSA-N

SMILES: N=1C=CC(C=2C=NN3C=C(C=NC23)C=4C=CC(=CC4)N5CCNCC5)=C6C=CC=CC16

Synonyms:

• 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
• 6-(4-(2-(Piperidin-1-Yl)Ethoxy)Phenyl)-3-(Pyridin-4-Yl)Pyrazolo[1,5-A]Pyrimidine
• Dm 3189
• Ldn 193189
• Quinoline, 4-[6-[4-(1-piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-

6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine

CAS: 1062368-24-4

• Formula: C₂₅H₂₂N₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 406.4824

LDN193189

CAS: 1062368-24-4

LDN193189 blocks BMP signaling by inhibiting ALK2/3; IC50: ALK1/2/3/6 = 0.8/0.8/5.3/16.7 nM.

• Formula: C₂₅H₂₂N₆
• Purity: 98% - 99.86%
• Color and Shape: Solid
• Molecular weight: 406.48

LDN 193189-d8

CAS: 1062368-24-4

• Formula: C₂₅D₈H₁₄N₆
• Color and Shape: Neat
• Molecular weight: 414.532

LDN 193189

CAS: 1062368-24-4

• Formula: C₂₅H₂₂N₆
• Color and Shape: Neat
• Molecular weight: 406.482

LDN 193189

CAS: 1062368-24-4

Inhibitor of ALK1, ALK2, ALK3 and ALK6 kinases and bone morphogenetic protein (BMP) pathway. LDN …

• Formula: C₂₅H₂₂N₆
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 406.48 g/mol

LDN 193189 (DISCONTINUED)

CAS: 1062368-24-4

• Formula: C₂₅H₂₂N₆
• Molecular weight: 406.48