CAS 1062368-24-4

4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline

Description:

4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline, identified by its CAS number 1062368-24-4, is a synthetic organic compound that belongs to a class of heterocyclic compounds. This substance features a complex molecular structure that includes a quinoline core fused with a pyrazolo-pyrimidine moiety, along with a piperazine substituent. The presence of these heterocycles suggests potential biological activity, particularly in medicinal chemistry, where such compounds are often explored for their pharmacological properties. The piperazine group may enhance solubility and bioavailability, making it a candidate for drug development. The compound's characteristics, including its molecular weight, solubility, and stability, would be influenced by its specific functional groups and overall structure. Additionally, its potential applications could span various therapeutic areas, including oncology and neurology, depending on its mechanism of action and interaction with biological targets. Further studies would be necessary to elucidate its full profile, including toxicity and efficacy in biological systems.

Formula: C₂₅H₂₂N₆

InChI: InChI=1S/C25H22N6/c1-2-4-24-22(3-1)21(9-10-27-24)23-16-29-31-17-19(15-28-25(23)31)18-5-7-20(8-6-18)30-13-11-26-12-14-30/h1-10,15-17,26H,11-14H2

InChI key: InChIKey=CDOVNWNANFFLFJ-UHFFFAOYSA-N

SMILES: C1(=C2N(N=C1)C=C(C=N2)C3=CC=C(C=C3)N4CCNCC4)C=5C6=C(N=CC5)C=CC=C6

Synonyms:

• 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
• 6-(4-(2-(Piperidin-1-Yl)Ethoxy)Phenyl)-3-(Pyridin-4-Yl)Pyrazolo[1,5-A]Pyrimidine
• Dm 3189
• Ldn 193189
• Quinoline, 4-[6-[4-(1-piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-

Quinoline, 4-​[6-​[4-​(1-​piperazinyl)​phenyl]​pyrazolo[1,​5-​a]​pyrimidin-​3-​yl]​-

CAS: 1062368-24-4

Formula: C₂₅H₂₂N₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 406.4824

Ref: IN-DA008THA

LDN193189

CAS: 1062368-24-4

LDN193189

Purity: ≥98%

Molecular weight: 406.48g/mol

Ref: 54-BUP09661

4-(6-(4-(Piperazin-1-Yl)Phenyl)Pyrazolo[1,5-A]Pyrimidin-3-Yl)Quinoline

CAS: 1062368-24-4

4-(6-(4-(Piperazin-1-Yl)Phenyl)Pyrazolo[1,5-A]Pyrimidin-3-Yl)Quinoline

Purity: 98%

Molecular weight: 406.48g/mol

Ref: 54-OR1023231

LDN193189

CAS: 1062368-24-4

LDN193189 blocks BMP signaling by inhibiting ALK2/3; IC50: ALK1/2/3/6 = 0.8/0.8/5.3/16.7 nM.

Formula: C₂₅H₂₂N₆

Purity: 98% - 99.86%

Color and Shape: Solid

Molecular weight: 406.48

Ref: TM-T1935

LDN 193189-d8

Controlled Product

CAS: 1062368-24-4

Formula: C₂₅D₈H₁₄N₆

Color and Shape: Neat

Molecular weight: 414.532

Ref: TR-P480132

LDN 193189

Controlled Product

CAS: 1062368-24-4

Formula: C₂₅H₂₂N₆

Color and Shape: Neat

Molecular weight: 406.482

Ref: TR-P480130

LDN 193189

CAS: 1062368-24-4

Inhibitor of ALK1, ALK2, ALK3 and ALK6 kinases and bone morphogenetic protein (BMP) pathway. LDN 1931189 is a dorsomorphin derivative that inhibits BMP-mediated activation of Smad, Akt and p38 signalling. LDN 193189 promotes differentiation of human pluripotent cells into PAX6+ anterior neural ectoderm. In combination with basic fibroblast growth factor (FGF2), LDN 193189 promotes differentiation of mouse pluripotent stem cells into inner ear sensory epithelium.

Formula: C₂₅H₂₂N₆

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 406.48 g/mol

Ref: 3D-FP43352