CAS 106461-41-0: 2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one

Description: 2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one, with CAS number 106461-41-0, is a synthetic organic compound characterized by its complex structure, which includes a triazole ring, piperazine moiety, and multiple aromatic systems. This compound exhibits properties typical of triazole derivatives, such as potential biological activity, particularly in the realm of pharmacology. Its structure suggests it may interact with various biological targets, making it of interest in medicinal chemistry. The presence of the hydroxyphenyl group may enhance solubility and bioactivity, while the piperazine ring is often associated with psychoactive properties. Additionally, the compound's lipophilicity, influenced by the isopropyl group, may affect its pharmacokinetics and distribution in biological systems. Overall, this compound's unique structural features position it as a candidate for further research in drug development and therapeutic applications.

Formula: C₂₂H₂₇N₅O₂

InChI: InChI=1S/C22H27N5O2/c1-3-17(2)27-22(29)26(16-23-27)20-6-4-18(5-7-20)24-12-14-25(15-13-24)19-8-10-21(28)11-9-19/h4-11,16-17,28H,3,12-15H2,1-2H3

InChI key: InChIKey=FFAQILVGBAELHN-UHFFFAOYSA-N

SMILES: O=C1N(C=NN1C(C)CC)C2=CC=C(C=C2)N3CCN(C4=CC=C(O)C=C4)CC3

Synonyms:

• 1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one
• 1-Sec Butyl-[4[4(4-Hydroxyphenyl)-1-Piperazinyl]-Phenyl]-1,2,4-Triazolo-5-One
• 2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]-phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
• 2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazole-3-one
• 2-Butan-2-yl-4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-1,2,4-triazol-3-one
• 2-Sec-Butyl-4-[4-[4-(4-Hydroxyphenyl)Piperazin-1-Yl]Phenyl]-2,4-Dihydro-[1,2,4]Triazol-3-One
• 2-sec-butyl-4-{4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl}-2h-1,2,4-triazol-3(4H)-one
• 3H-1,2,4-Triazol-3-one, 2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-
• 4-{4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl}-2-(1-methylpropyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
• T 1330

2-(Sec-butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

CAS: 106461-41-0

• Formula: C₂₂H₂₇N₅O₂
• Purity: %
• Color and Shape: Solid
• Molecular weight: 393.4821

5-LOX inhibitor

CAS: 106461-41-0

• Purity: ≥98%
• Molecular weight: 393.48g/mol

2-(Sec-butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

CAS: 106461-41-0

• Purity: 98%+
• Molecular weight: 393.48g/mol

Itraconazole Impurity 10

CAS: 106461-41-0

• Formula: C₂₂H₂₇N₅O₂
• Color and Shape: Off-White Solid
• Molecular weight: 393.49

4-[4-[4-(4-Hydroxyphenyl)piperazin-1-yl]phenyl]-2-[(1RS)-1-methylpropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one

CAS: 106461-41-0

• Formula: C₂₂H₂₇N₅O₂
• Color and Shape: Neat
• Molecular weight: 393.48

2,4-Dihydro-4-[4-[4-(4-hydroxyphenyl]-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one

CAS: 106461-41-0

Applications An intermediate in the synthesis of Itraconazole.

• Formula: C₂₂H₂₇N₅O₂
• Color and Shape: Neat
• Molecular weight: 393.48

2-(Sec-butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

CAS: 106461-41-0

• Purity: 97%
• Molecular weight: 393.4909973144531

5-LOX inhibitor

CAS: 106461-41-0

5-LOX inhibitor (1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one) is an itraconazole impurity, a LOX-5 inhibitor.

• Formula: C₂₂H₂₇N₅O₂
• Purity: 98.01%
• Color and Shape: Solid
• Molecular weight: 393.48

Itraconazole Hydroxy Isobutyltriazolone Impurity

CAS: 106461-41-0

• Formula: C₂₂H₂₇N₅O₂
• Molecular weight: 393.49