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CAS 106560-14-9

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Faropenem

Description:
Faropenem is a synthetic antibiotic belonging to the class of penems, which are beta-lactam antibiotics. It is characterized by its broad-spectrum activity against various Gram-positive and Gram-negative bacteria, making it effective in treating a range of infections. Faropenem is notable for its stability against certain beta-lactamases, enzymes produced by bacteria that can inactivate many penicillins and cephalosporins. This stability enhances its therapeutic potential, particularly in resistant bacterial strains. The compound is typically administered orally, which is advantageous for outpatient treatment scenarios. Its mechanism of action involves inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Faropenem has been studied for its efficacy in treating respiratory tract infections, skin infections, and other bacterial diseases. However, like all antibiotics, its use must be judicious to prevent the development of resistance. Overall, Faropenem represents an important option in the antibiotic arsenal, particularly in the context of increasing antibiotic resistance.
Formula:C12H15NO5S
InChI:InChI=1S/C12H15NO5S/c1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6/h5-7,11,14H,2-4H2,1H3,(H,16,17)/t5-,6-,7+,11-/m1/s1
InChI key:InChIKey=HGGAKXAHAYOLDJ-FHZUQPTBSA-N
SMILES:C(O)(=O)C=1N2[C@@]([C@@]([C@@H](C)O)(C2=O)[H])(SC1[C@H]3CCCO3)[H]
Synonyms:
  • (+)-(5R,6S)-6-((1R)-1-Hydroxyethyl)-7-oxo-3-((2R)-tetrahydro-2-furyl)-4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
  • (5R,6S)-6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydrofuran-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  • (5R,6S,8R,2′R)-2-(2′-tetrahydrofuryl)-6-(1-hydroxyethyl)-2-penem-3-carboxylic acid
  • 4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-, [5R-[3(R*),5α,6α(R*)]]-
  • 4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-, (5R,6S)-
  • Faropenem Sodium Hemipentahydrate
  • Fropenem
  • Faropenem
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