CAS 106685-40-9
:Adapalene
Description:
Adapalene is a synthetic retinoid, primarily used in dermatology for the treatment of acne vulgaris. It is characterized by its ability to modulate cellular differentiation, keratinization, and inflammatory processes in the skin. Adapalene exhibits a high affinity for retinoic acid receptors, which contributes to its effectiveness in promoting cell turnover and preventing the formation of comedones. The compound is typically formulated as a topical gel or cream, allowing for localized treatment with minimal systemic absorption. Adapalene is known for its stability in light and heat, making it suitable for various formulations. Common side effects may include skin irritation, dryness, and peeling, particularly during the initial stages of treatment. Unlike some other retinoids, adapalene is less likely to cause photosensitivity, allowing for daytime application. Its efficacy and safety profile have made it a popular choice in acne management, often recommended for both adolescents and adults.
Formula:C28H28O3
InChI:InChI=1S/C28H28O3/c1-31-26-7-6-23(21-2-3-22-12-24(27(29)30)5-4-20(22)11-21)13-25(26)28-14-17-8-18(15-28)10-19(9-17)16-28/h2-7,11-13,17-19H,8-10,14-16H2,1H3,(H,29,30)
InChI key:InChIKey=LZCDAPDGXCYOEH-UHFFFAOYSA-N
SMILES:O(C)C1=C(C23CC4CC(C2)CC(C3)C4)C=C(C=C1)C5=CC6=C(C=C5)C=C(C(O)=O)C=C6
Synonyms:- 2-Naphthalenecarboxylic acid, 6-(4-methoxy-3-tricyclo[3.3.1.1<sup>3,7</sup>]dec-1-ylphenyl)-
- 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoic acid
- 6-(4-Methoxy-3-tricyclo[3.3.1.1<sup>3,7</sup>]dec-1-ylphenyl)-2-naphthalenecarboxylic acid
- 6-[3-(1-Adamantyl)-4-Methoxyphenyl]-2-Naphthalene Carboxylic Acid
- 6-[3-(1-Adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid
- 6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthalenecarboxylic acid
- 6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthoic acid
- 6-[4-Methoxy-3-(Tricyclo[3.3.1.1~3,7~]Dec-1-Yl)Phenyl]Naphthalene-2-Carboxylic Acid
- Aclene
- Aclene Gel
- Adapalen
- CD 271 (pharmaceutical)
- Cd-271
- Differin
- Differin Gel
- Adapalene
- 6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid
- See more synonyms
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Found 19 products.
ADAPALENE CRS
CAS:<p>ADAPALENE CRS</p>Formula:C28H28O3Color and Shape:White. Powder.Molecular weight:412.5201ADAPALENE FOR PEAK IDENTIFICATION CRS
CAS:<p>ADAPALENE FOR PEAK IDENTIFICATION CRS</p>Formula:C28H28O3Molecular weight:412.5201Adapalene
CAS:Carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides etc, nesoiFormula:C28H28O3Color and Shape:White Off-White PowderMolecular weight:412.203846-[3-(1-Adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid
CAS:Formula:C28H28O3Purity:99%Color and Shape:SolidMolecular weight:412.5201Ref: IN-DA0038BR
1g56.00€5g113.00€10g168.00€25g240.00€50g557.00€100gTo inquire250gTo inquire500gTo inquire100mg25.00€250mg30.00€Adapalene
CAS:<p>Adapalene (CD271) is a dual RAR and RXR agonist, utilized in the treatment of skin conditions.</p>Formula:C28H28O3Purity:99.53% - 99.76%Color and Shape:White To Off-White Crystalline PowderMolecular weight:412.526-(3-(Adamantan-1-Yl)-4-Methoxyphenyl)-2-Naphthoic Acid
CAS:6-(3-(Adamantan-1-Yl)-4-Methoxyphenyl)-2-Naphthoic AcidPurity:99%Molecular weight:412.52g/molAdapalene-13C6
CAS:Formula:C2213C6H28O3Color and Shape:White To Off-White SolidMolecular weight:418.48Adapalene
CAS:Formula:C28H28O3Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:412.53Adapalene
CAS:Formula:C28H28O3Purity:≥ 99%Color and Shape:White to off-white crystalline powderMolecular weight:412.526-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoic acid
CAS:Controlled Product<p>Agonist of retinoic acid receptors (RAR-? and RAR-?); pro-apoptotic</p>Formula:C28H28O3Purity:Min. 95%Color and Shape:PowderMolecular weight:412.52 g/molAdapalene - Bio-X ™
CAS:Controlled Product<p>This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>Formula:C28H28O3Purity:Min. 95%Color and Shape:PowderMolecular weight:412.52 g/molAdapalene
CAS:Controlled Product<p>Applications Retinoid selective for retinoic acid receptor (RAR) subtypes β and γ. Antiacne.<br>References Griffiths, C.E.M., et al.: J. Invest. Dermatol., 101, 325 (1993), Bernard, B.A., et al.: Skin Pharmacol., 6, 61 (1993), Waugh, J., et al.: Drugs, 64, 1465 (2004),<br></p>Formula:C28H28O3Color and Shape:WhiteMolecular weight:412.52Adapalene-1’,4’-dione
CAS:Controlled ProductFormula:C28H26O5Color and Shape:NeatMolecular weight:442.503
![6-[3-(1-Adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0038BR.jpg&w=3840&q=75)
