CAS 106685-40-9: Adapalene

Description: Adapalene is a synthetic retinoid, primarily used in dermatology for the treatment of acne vulgaris. It is characterized by its ability to modulate cellular differentiation, keratinization, and inflammatory processes in the skin. Adapalene exhibits a high affinity for retinoic acid receptors, which contributes to its effectiveness in promoting cell turnover and preventing the formation of comedones. The compound is typically formulated as a topical gel or cream, allowing for localized treatment with minimal systemic absorption. Adapalene is known for its stability in light and heat, making it suitable for various formulations. Common side effects may include skin irritation, dryness, and peeling, particularly during the initial stages of treatment. Unlike some other retinoids, adapalene is less likely to cause photosensitivity, allowing for daytime application. Its efficacy and safety profile have made it a popular choice in acne management, often recommended for both adolescents and adults.

Formula: C₂₈H₂₈O₃

InChI: InChI=1S/C28H28O3/c1-31-26-7-6-23(21-2-3-22-12-24(27(29)30)5-4-20(22)11-21)13-25(26)28-14-17-8-18(15-28)10-19(9-17)16-28/h2-7,11-13,17-19H,8-10,14-16H2,1H3,(H,29,30)

InChI key: InChIKey=LZCDAPDGXCYOEH-UHFFFAOYSA-N

SMILES: O=C(O)C=1C=CC2=CC(=CC=C2C1)C=3C=CC(OC)=C(C3)C45CC6CC(CC(C6)C4)C5

Synonyms:

• 2-Naphthalenecarboxylic acid, 6-(4-methoxy-3-tricyclo[3.3.1.1^3,7]dec-1-ylphenyl)-
• 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoic acid
• 6-(4-Methoxy-3-tricyclo[3.3.1.1^3,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid
• 6-[3-(1-Adamantyl)-4-Methoxyphenyl]-2-Naphthalene Carboxylic Acid
• 6-[3-(1-Adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid
• 6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthalenecarboxylic acid
• 6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthoic acid
• 6-[4-Methoxy-3-(Tricyclo[3.3.1.1~3,7~]Dec-1-Yl)Phenyl]Naphthalene-2-Carboxylic Acid
• Aclene
• Aclene Gel
• Adapalen
• CD 271 (pharmaceutical)
• Cd-271
• Differin
• Differin Gel
• Adapalene
• 6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid
• 2-Naphthalenecarboxylic acid, 6-(4-methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-

Adapalene

CAS: 106685-40-9

• Formula: C₂₈H₂₈O₃
• Purity: 99.7%
• Color and Shape: White
• Molecular weight: 412.20384

Adapalene CRS

CAS: 106685-40-9

• Formula: C₂₈H₂₈O₃
• Color and Shape: White. Powder.
• Molecular weight: 412.5201

Adapalene for peak identification CRS

CAS: 106685-40-9

• Formula: C₂₈H₂₈O₃
• Molecular weight: 412.5201

Adapalene

CAS: 106685-40-9

Carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides etc, nesoi

• Formula: C₂₈H₂₈O₃
• Color and Shape: White Off-White Powder
• Molecular weight: 412.20384

Adapalene

CAS: 106685-40-9

Adapalene (CD271) is a dual RAR and RXR agonist, utilized in the treatment of skin …

• Formula: C₂₈H₂₈O₃
• Purity: 99.53% - 99.76%
• Color and Shape: White To Off-White Crystalline Powder
• Molecular weight: 412.52

6-[3-(1-Adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid

CAS: 106685-40-9

• Formula: C₂₈H₂₈O₃
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 412.5201

6-(3-(Adamantan-1-Yl)-4-Methoxyphenyl)-2-Naphthoic Acid

CAS: 106685-40-9

• Purity: 99%
• Molecular weight: 412.52g/mol

Adapalene

CAS: 106685-40-9

• Formula: C₂₈H₂₈O₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 412.53

Adapalene-13C6

CAS: 106685-40-9

• Formula: C₂₂₁₃C₆H₂₈O₃
• Color and Shape: White To Off-White Solid
• Molecular weight: 418.48

Adapalene

CAS: 106685-40-9

• Purity: 99.76%
• Molecular weight: 412.52g/mol

Adapalene

CAS: 106685-40-9

• Formula: C₂₈H₂₈O₃
• Color and Shape: Neat
• Molecular weight: 412.52

Adapalene

CAS: 106685-40-9

• Formula: C₂₈H₂₈O₃
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 412.53

Adapalene

CAS: 106685-40-9

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₂₈H₂₈O₃
• Color and Shape: White to light yellow, Crystalline powder
• Molecular weight: 412.53

Adapalene

CAS: 106685-40-9

• Formula: C₂₈H₂₈O₃
• Color and Shape: Neat
• Molecular weight: 412.52

Adapalene

CAS: 106685-40-9

• Formula: C₂₈H₂₈O₃
• Purity: ≥ 99%
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 412.52

Adapalene-d15

CAS: 106685-40-9

• Formula: C₂₈H₁₃O₃D₁₅
• Molecular weight: 427.62

6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoic acid

CAS: 106685-40-9

Agonist of retinoic acid receptors (RAR-? and RAR-?); pro-apoptotic

• Formula: C₂₈H₂₈O₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 412.52 g/mol

Adapalene - Bio-X ™

CAS: 106685-40-9

This product is part of our Bio-X ™ Range. These products are aimed at life …

• Formula: C₂₈H₂₈O₃
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 412.52 g/mol

Adapalene

CAS: 106685-40-9

Applications Retinoid selective for retinoic acid receptor (RAR) subtypes β and γ. Antiacne. References Griffiths, …

• Formula: C₂₈H₂₈O₃
• Color and Shape: White
• Molecular weight: 412.52

Adapalene-1’,4’-dione

CAS: 106685-40-9

• Formula: C₂₈H₂₆O₅
• Color and Shape: Neat
• Molecular weight: 442.503