CAS 106730-54-5: Olprinone

Description: Olprinone is a pharmacological agent primarily classified as a phosphodiesterase inhibitor, specifically targeting phosphodiesterase type 3 (PDE3). This compound is known for its vasodilatory and inotropic effects, making it useful in the treatment of heart failure and other cardiovascular conditions. Chemically, Olprinone is characterized by its ability to increase intracellular cyclic AMP levels, which enhances cardiac contractility and promotes vasodilation. It is typically administered intravenously and is noted for its relatively rapid onset of action. The substance is often studied for its potential benefits in improving cardiac output and reducing systemic vascular resistance. In terms of safety and side effects, Olprinone may cause hypotension, arrhythmias, or other cardiovascular effects, necessitating careful monitoring during administration. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are critical for understanding its therapeutic applications and potential interactions with other medications. Overall, Olprinone represents a significant option in the management of acute heart failure and related conditions.

Formula: C₁₄H₁₀N₄O

InChI: InChI=1S/C14H10N4O/c1-9-12(6-11(7-15)14(19)17-9)10-2-3-13-16-4-5-18(13)8-10/h2-6,8H,1H3,(H,17,19)

InChI key: InChIKey=JPAWFIIYTJQOKW-UHFFFAOYSA-N

SMILES: N#CC1=CC(C=2C=CC3=NC=CN3C2)=C(NC1=O)C

Synonyms:

• 1,2-Dihydro-5-Imidazo(1,2-Alpha)Pyridin-6-Yl-6-Methyl-2-Oxonicotinonitrile
• 1,2-Dihydro-5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxonicotinonitrile
• 1,2-Dihydro-5-imidazo[1,2-α]pyridin-6-yl-6-methyl-2-oxo-3-pyridinecarbonitrile
• 3-Pyridinecarbonitrile, 1,2-dihydro-5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-
• 5-(1,7-Diazabicyclo[4.3.0]Nona-2,4,6,8-Tetraen-3-Yl)-6-Methyl-2-Oxo-1H-Pyridine-3-Carbonitrile
• 5-(Imidazo[1,2-A]Pyridin-6-Yl)-6-Methyl-2-Oxo-1,2-Dihydropyridine-3-Carbonitrile
• Imidazo[1,2-a]pyridine, 3-pyridinecarbonitrile deriv.
• Loprinone
• Olprinone(Loprinone)

3-Pyridinecarbonitrile,1,2-dihydro-5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-

CAS: 106730-54-5

• Formula: C₁₄H₁₀N₄O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 250.2554

Olprinone

CAS: 106730-54-5

• Formula: C₁₄H₁₀N₄O
• Molecular weight: 250.26

Olprinone

CAS: 106730-54-5

• Formula: C₁₄H₁₀N₄O
• Molecular weight: 250.26

Olprinone

CAS: 106730-54-5

Olprinone (Loprinone)(Loprinone) is a selective phosphodiesterase 3 (PDE3) inhibitor.Olprinone has been reported to improve microcirculation …

• Formula: C₁₄H₁₀N₄O
• Purity: 99.87%
• Color and Shape: Solid
• Molecular weight: 250.26

5-(Imidazo[1,2-a]pyridin-6-yl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

CAS: 106730-54-5

• Purity: 95.0%
• Molecular weight: 250.26100158691406

Olprinone

CAS: 106730-54-5

Olprinone is a drug that is used to treat congestive heart failure. It is an …

• Formula: C₁₄H₁₀N₄O
• Purity: Min. 95%
• Molecular weight: 250.26 g/mol