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CAS 1067644-15-8

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Found 2 products.
  • N-Methyl Naltrexone Glucuronide
    TLC
    + Info

    N-Methyl Naltrexone Glucuronide

    CAS:
    Formula:C27H33NO10
    Molecular weight:531.56

    Ref: 4Z-N-0126

    5mg
    To inquire
    10mg
    2,427.00€
    25mg
    4,368.00€
    50mg
    7,220.00€
    100mg
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  • N-Methyl Naltrexone Glucuronide
    TRC
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    N-Methyl Naltrexone Glucuronide

    Controlled Product
    CAS:
    <p>Applications N-Methyl Naltrexone Glucuronide is metabolite of Naltrexone (N285750). Methylnaltrexone (MNTX; M320350), a selective μ-opioid receptor (MOR) antagonist, functions as a peripherally acting receptor antagonist in tissues of the gastrointestinal tract. When opiates activate μ-opioid receptors (MORs) they trigger signaling pathways that lead to tolerance and hyperalgesia. Methylnaltrexone (M320350) is positively charged and therefore does not cross the blood brain barier. Mice given morphine with methylnaltrexone experienced pain relief without degeloping tolerance.<br>References Wall, M., et al.: Drug Metab. Dispos., 12, 677 (1984), Jones, D., et al.: .: Bioorg. Med. Chem., 13, 6727 ( 2005), Chen, T., et al.: Drugs Future, 32, 771 (2007); Chem. and Eng. News p.4 Jan. 23, (2017)<br></p>
    Formula:C27H34NO10
    Color and Shape:Neat
    Molecular weight:532.56

    Ref: TR-M493190

    10mg
    2,087.00€