CAS 106864-37-3: Fmoc-Tyr(SO3H)-OH . sodium salt
Description:Fmoc-Tyr(SO3H)-OH, sodium salt, is a derivative of tyrosine, an amino acid, modified with a fluorenylmethyloxycarbonyl (Fmoc) protecting group and a sulfonic acid group (SO3H). This compound is primarily used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), where the Fmoc group serves as a protective group for the amino functionality, allowing for selective deprotection and coupling reactions. The sulfonic acid group enhances the solubility of the compound in aqueous solutions and can also influence the overall charge and reactivity of the molecule. As a sodium salt, it is typically more soluble in water compared to its free acid form, facilitating its use in various biochemical applications. The presence of the sulfonic acid group may also impart unique properties, such as increased polarity and potential interactions with other biomolecules. Overall, Fmoc-Tyr(SO3H)-OH, sodium salt, is a valuable reagent in the field of organic and medicinal chemistry, particularly in the synthesis of biologically active peptides.
Formula:C24H20NNaO8S
InChI:InChI=1S/C24H21NO8S.Na/c26-23(27)22(13-15-9-11-16(12-10-15)33-34(29,30)31)25-24(28)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21;/h1-12,21-22H,13-14H2,(H,25,28)(H,26,27)(H,29,30,31);/t22-;/m0./s1
InChI key:InChIKey=NRWWLTREFOXIDB-FTBISJDPSA-N
SMILES:[Na].O=C(OCC1C=2C=CC=CC2C=3C=CC=CC31)NC(C(=O)O)CC4=CC=C(OS(=O)(=O)O)C=C4
- Synonyms:
- <span class="text-smallcaps">L</span>-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, hydrogen sulfate (ester), monosodium salt
- <span class="text-smallcaps">L</span>-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-sulfo-, sodium salt (1:1)
- Fmoc-Tyr(SO3Na)-OH.H2O
- Fmoc-Tyr(SO3Na)-OH・H2O
