CAS 1069112-52-2

N-Methyl-6-(4-nitrophenoxy)-4-pyrimidinamine

Controlled Product

CAS: 1069112-52-2

Applications N-Methyl-6-(4-nitrophenoxy)-4-pyrimidinamine is an intermediate in the synthesis of N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N'-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea (E926495), which is an inhibitor of RET, FLT3, KDR, c-Abl and c-Kit. Also, it prevent the growth of human thyroid cancer cells.
References Weisberg, E., et al.: Genes Cancer, 1, 1021-1032 (2010);

Formula: C₁₁H₁₀N₄O₃

Color and Shape: Neat

Molecular weight: 246.22

Ref: TR-M106910