CAS 106916-16-9

N-DESPROPYL ROPINIROLE

Description:

N-Despropyl Ropinirole is a chemical compound that serves as a metabolite of the drug Ropinirole, which is primarily used in the treatment of Parkinson's disease and restless legs syndrome. This substance is characterized by its structural modification, where the propyl group is removed from the Ropinirole molecule, resulting in a simpler structure. N-Despropyl Ropinirole exhibits similar pharmacological properties to its parent compound, although it may have different potency and efficacy. It is typically classified as a dopamine agonist, interacting with dopamine receptors in the brain, particularly the D2 receptor subtype. The compound is often studied for its role in understanding the metabolism and pharmacokinetics of Ropinirole, as well as its potential effects on the central nervous system. In terms of physical properties, N-Despropyl Ropinirole is expected to be a solid or liquid at room temperature, with specific solubility characteristics that may influence its bioavailability and therapeutic effects. Safety and toxicity profiles are also important considerations in its study and application.

Formula: C₁₃H₁₈N₂O

Synonyms:

• 1,3-Dihydro-4-[2-(propylamino)ethyl]-2H-indol-2-one
• 4-[2-(Propylamino)ethyl]-1,3-dihydro-2H-indol-2-one
• Skf 10455
• Skf 104557
• N-Despropyl Ropinirole Discontinued see product # D297380

4-(2-(Propylamino)ethyl)indolin-2-one

CAS: 106916-16-9

Formula: C₁₃H₁₈N₂O

Purity: 97%

Color and Shape: Solid

Molecular weight: 218.2948

Ref: IN-DA0082UK

N-Despropyl Ropinirole

CAS: 106916-16-9

Formula: C₁₃H₁₈N₂O

Molecular weight: 218.30

Ref: 4Z-R-133

Relugolix Impurity 44 Disodium Salt

CAS: 106916-16-9, 173990-76-6

Formula: C₅₀H₅₀F₄N₆O₈S₂·2Na

Molecular weight: 1003.10 2*22.99

Ref: 4Z-R-139046

N-Despropyl Ropinirole

Controlled Product

CAS: 106916-16-9

Stability Hygroscopic
Applications A metabolite of Ropinirole.
References Coldwell, M., et al.: Br. J. Pharmacol., 127, 1135 (1999), Ramji, J., et al.: Xenobiotica, 29, 311 (1999)

Formula: C₁₃H₁₈N₂O

Color and Shape: Neat

Molecular weight: 218.29

Ref: TR-D297380

4-(2-(Propylamino)ethyl)indolin-2-one

CAS: 106916-16-9

Purity: 97%

Molecular weight: 218.3000031

Ref: 10-F765890

SKF-104557

CAS: 106916-16-9

N-Despropyl ropinirole, a ropinirole metabolite, enhances CHO cell acidification via D2/D3/D4 receptors; also a ropinirole impurity. EC50: 0.63-1.23 µM.

Formula: C₁₃H₁₈N₂O

Color and Shape: Solid

Molecular weight: 218.29

Ref: TM-T72003