CAS 106931-78-6

Fluocinolone Acetonide-21-carboxylic Acid

Description:

Fluocinolone Acetonide-21-carboxylic Acid, with the CAS number 106931-78-6, is a synthetic corticosteroid derivative primarily used for its anti-inflammatory and immunosuppressive properties. This compound is characterized by its potent glucocorticoid activity, which makes it effective in treating various dermatological conditions, such as eczema and psoriasis. The structure of Fluocinolone Acetonide-21-carboxylic Acid features a fluorinated steroid backbone, contributing to its enhanced stability and efficacy. It is typically administered topically in formulations designed to minimize systemic absorption while maximizing local therapeutic effects. The compound exhibits a favorable pharmacokinetic profile, allowing for effective management of inflammation with a reduced risk of side effects commonly associated with systemic corticosteroids. Additionally, it is important to note that, like other corticosteroids, prolonged use may lead to skin atrophy or other local adverse effects, necessitating careful monitoring during treatment. Overall, Fluocinolone Acetonide-21-carboxylic Acid is a valuable agent in dermatological therapy, balancing efficacy with safety when used appropriately.

Formula: C₂₄H₂₈F₂O₇

Synonyms:

• Fluocinolone Acetonide EP Impurity A
• Fluocinolone Acetonide EP Impurity A (Fluocinolone Acetonide-21-Carboxylic Acid)
• Fluocinolone Acetonide Impurity 1 (Fluocinolone Acetonide EP Impurity A）(Fluocinolone Acetonide-21-Carboxylic Acid)
• Fluocinolone Impurity A
• 6α,9-Difluoro-11β-hydroxy-16α,17-(1-methylethylidenedioxy)-3,20-dioxopregna-1,4-dien-21-oic Acid
• KUVGGCPFHYXHKI-BDQUCZKRSA-N
• UNII-QUA72C1T6F
• (6alpha,11beta,16alpha,17alpha)-6,9-Difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-3,20-dioxo-pregna-1,4-dien-21-oic acid
• Fluocinolone Acetonide-21-carboxylic Acid (>90%)
• Fluocinolone Acetonide-21-carboxylic Acid
• Pregna-1,4-dien-21-oic acid, 6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-3,20-dioxo-, (6α,11β,16α,17α)- (9CI)

Fluocinolone Acetonide EP Impurity A

CAS: 106931-78-6

Formula: C₂₄H₂₈F₂O₇

Molecular weight: 466.48

Ref: ST-EA-CP-F56001

Fluocinolone Acetonide EP Impurity A (Fluocinolone Acetonide-21-Carboxylic Acid)

CAS: 106931-78-6

Formula: C₂₄H₂₈F₂O₇

Color and Shape: White To Off-White Solid

Molecular weight: 466.48

Ref: 4Z-F-118004

Fluocinolone Acetonide-21-carboxylic Acid (>90%)

CAS: 106931-78-6

Impurity Fluocinolone Acetonide EP Impurity A
Applications Fluocinolone Acetonide-21-carboxylic Acid, is a derivative of Fluocinolone Acetonide (F455800), which is a Corticosteroid, used in dermatology to reduce skin inflammation and relieve itching
References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),

Formula: C₂₄H₂₈F₂O₇

Purity: >90%

Color and Shape: Off White

Molecular weight: 466.47

Ref: TR-F455815

Fluocinolone acetonide-21-carboxylic acid

CAS: 106931-78-6

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Formula: C₂₄H₂₈F₂O₇

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 466.47 g/mol

Ref: 3D-FF183645