CAS 106939-34-8

LEVOFLOXACIN ACID ESTER

Description:

Levofloxacin acid ester, with the CAS number 106939-34-8, is a derivative of levofloxacin, which is a fluoroquinolone antibiotic. This compound exhibits antibacterial properties, primarily targeting bacterial DNA gyrase and topoisomerase IV, which are essential for bacterial DNA replication and transcription. Levofloxacin acid ester is characterized by its ability to inhibit the growth of a broad spectrum of Gram-positive and Gram-negative bacteria, making it effective in treating various infections. The compound is typically administered in its active form, and its pharmacokinetics may be influenced by factors such as solubility and stability. In terms of physical properties, levofloxacin acid ester is generally a crystalline solid, with specific melting and boiling points that can vary based on purity and formulation. Safety and efficacy are critical considerations in its use, and it is essential to monitor for potential side effects, including gastrointestinal disturbances and effects on the central nervous system. Overall, levofloxacin acid ester plays a significant role in antimicrobial therapy, particularly in treating respiratory and urinary tract infections.

Formula: C₁₅H₁₃F₂NO₄

InChI: InChI=1/C15H13F2NO4/c1-3-21-15(20)9-5-18-7(2)6-22-14-11(17)10(16)4-8(12(14)18)13(9)19/h4-5,7H,3,6H2,1-2H3/t7-/m0/s1

InChI key: InChIKey=TZSXJUSNOOBBOP-ZETCQYMHSA-N

SMILES: O=C1C=2C=3N(C=C1C(OCC)=O)[C@@H](C)COC3C(F)=C(F)C2

Synonyms:

• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-, ethyl ester, (3S)-
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-, ethyl ester, (S)-
• Difluorocarboylic Acid Este
• Ethyl (3S)-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate
• Ethyl (S)-9,10-Difluoro-3-Methyl-7-Oxo-2,3-Dihydro-7H-Pyrido[1,2,3-De]-1,4-Benzoxazine-6-Carboxylate
• Ethyl 9,10-difluoro-3-(S)-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate
• ethyl (3S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate
• Levofloxacin cyclization ester
• Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido
• 9,10-Difluoro-3-(S)-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate
• Levofloxacin carboxylic acid, ethyl ester
• 7h-Pyrido[1,2,3-De]-1,4-Benzoxazine-6-Carboxylic Acid
• (S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Ethyl Ester
• (S)-Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxyla
• carboxylate
• (S)-Ethyl 9,10-difluoro-3-Methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate
• Levofloxacin Impurity 5
• (S)-Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carbox
• oxo-2,3-dihydro-7H-
• ethyl (S)-9,10-difluoro-3-methyl-7-
• (3S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacidethylester
• 7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBOXYLIC ACID, 9,10-DIFLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-, ETHYL ESTER
• [1,4]oxazino[2,3,4-ij]quinoline-6-

7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-, ethyl ester, (3s)-

CAS: 106939-34-8

Formula: C₁₅H₁₃F₂NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 309.2648

Ref: IN-DA007TQ0

(S)-Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

CAS: 106939-34-8

(S)-Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

Purity: 98%

Molecular weight: 309.268g/mol

Ref: 54-PC99767

Levofloxacin Impurity 10

CAS: 106939-34-8

Formula: C₁₅H₁₃F₂NO₄

Color and Shape: White To Off-White Solid

Molecular weight: 309.27

Ref: 4Z-L-2326

(S)-Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate

CAS: 106939-34-8

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 309.2690124511719

Ref: 10-F223912

(S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Ethyl Ester

CAS: 106939-34-8

Color and Shape: Neat

Ref: 86-MM0846.14

(S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Ethyl Ester

Controlled Product

CAS: 106939-34-8

Formula: C₁₅H₁₃F₂NO₄

Color and Shape: Off-White To Light Yellow

Molecular weight: 309.26

Ref: TR-D445748

Levofloxacin Impurity 10

CAS: 106939-34-8

Formula: C₁₅H₁₃F₂NO₄

Molecular weight: 309.3

Ref: ST-EA-CP-L17026

(S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid ethyl ester

CAS: 106939-34-8

(S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid ethyl ester is an acidic substance that can be produced by the amination of piperazine with chloroacetic acid. The reaction solution is heated to a temperature of about 120°C for about 30 minutes and then cooled to room temperature. The product precipitates as a white solid. This compound has been shown to have antibacterial activity against methicillin resistant Staphylococcus aureus (MRSA) in plates.

Formula: C₁₅H₁₃F₂NO₄

Purity: Min. 95%

Molecular weight: 309.26 g/mol

Ref: 3D-FD21854