CAS 106941-25-7
:Adefovir
Description:
Adefovir is an antiviral medication primarily used in the treatment of chronic hepatitis B virus (HBV) infections. It is a nucleotide analogue of adenosine monophosphate and functions by inhibiting viral DNA polymerase, thereby preventing the replication of the virus. Adefovir is characterized by its chemical formula, which includes a phosphonate group, contributing to its mechanism of action. The substance is typically administered in oral form and is known for its relatively low resistance profile compared to other antiviral agents. Common side effects may include nephrotoxicity, which necessitates monitoring of renal function during treatment. Adefovir is also notable for its potential use in combination therapies, enhancing the efficacy of treatment regimens for HBV. Its pharmacokinetics indicate that it has a long half-life, allowing for once-daily dosing. Overall, Adefovir represents a significant option in the management of chronic hepatitis B, particularly for patients who may not respond to other treatments.
Formula:C8H12N5O4P
InChI:InChI=1S/C8H12N5O4P/c9-7-6-8(11-3-10-7)13(4-12-6)1-2-17-5-18(14,15)16/h3-4H,1-2,5H2,(H2,9,10,11)(H2,14,15,16)
InChI key:InChIKey=SUPKOOSCJHTBAH-UHFFFAOYSA-N
SMILES:C(COCP(=O)(O)O)N1C=2C(N=C1)=C(N)N=CN2
Synonyms:- ((2-(6-Amino-9H-Purin-9-Yl)Ethoxy)Methyl)-Phosphonic Aci
- ((2-(6-Amino-9H-Purin-9-Yl)Ethoxy)Methyl)Phosphonic Acid
- ((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonicacid
- 2-(6-Amino-9H-Purin-9-Yl)Ethoxy]Methylphosphonic Acid
- 2-(6-Aminopurin-9-yl)ethoxymethylphosphonic acid
- 2-(6-amino-7H-purin-9-yl)ethoxymethylphosphonic acid
- 9-[2-(Phosphono Methoxy)Ethyl]Adenine
- 9-[2-(Phosphonomethoxy)ethyl]adenine
- 9-[2-(Phosphonomethoxy)ethyl]adenine(PMEA)
- 9-[2-Phosphonylmethoxyethyl]Adenine
- Gs 0393
- P-[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid
- Phosphonic acid, P-[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]-
- Phosphonic acid, [[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]-
- Pmea
- See more synonyms
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Found 12 products.
Adefovir
CAS:Formula:C8H12N5O4PPurity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:273.19Adefovir
CAS:Formula:C8H12N5O4PPurity:≥ 98.5%Color and Shape:White to off-white powderMolecular weight:273.19Adefovir
CAS:<p>Adefovir: acyclic nucleoside phosphonate, reverse transcriptase inhibitor for hepatitis B and herpes treatment.</p>Formula:C8H12N5O4PPurity:99.56%Color and Shape:White To Off-White PowderMolecular weight:273.19Adefovir
CAS:Controlled Product<p>Applications Adefovir is a more toxic analog of Tenofovir. Also, it is used with entecavir as similar efficacy in treating chronic hepatitis B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhao, X., et al.: Sci. Rep., 7, 46344 (2017); Huang, J., et al.: Zhongguo Yaoye, 25, 29-31 (2016)<br></p>Formula:C8H12N5O4PColor and Shape:Off White SolidMolecular weight:273.19Adefovir
CAS:Adefovir is an acyclic phosphonate nucleotide analog of dAMP. It has anti-viral activity against HIV-1 and HBV by inhibiting reverse transcriptase and polymerase activity, respectively. Adefovir has also demonstrated improved antiviral activity when combined with other HBV drugs.Formula:C8H12N5O4PPurity:Min. 95%Color and Shape:White PowderMolecular weight:273.19 g/molAdefovir - Bio-X ™
CAS:<p>Adefovir is an antiviral drug that is used for the treatment of hepatitis B infections. This drug works by blocking the enzyme reverse transcriptase, therefore preventing the replication of the virus in the body.</p>Formula:C8H12N5O4PPurity:Min. 95%Color and Shape:PowderMolecular weight:273.19 g/mol((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid
CAS:Formula:C8H12N5O4PPurity:95%Color and Shape:SolidMolecular weight:273.189
